Abstract：
The preparation of nanozymes with high specific activity is highly important for various applications. However, only a few nanozymes have specific activities comparable to natural enzymes. Herein, novel Pt-on-Rh hollow nanorods (PtRh HNRs) were developed, in which surface Pt exhibited adjustable dispersity and interior Rh served as the support. The optimized PtRh HNRs demonstrated high-performance peroxidase (POD)-like activity, with a specific activity as high as 1352 U mg-1, which was 3.86 times that of their monometallic Pt counterparts. Density functional theory (DFT) calculations illustrated that the presence of Rh decreased the energy barrier of the rate-determining step. When PtRh HNRs were used as nanozymes in the colorimetric detection of hydrogen peroxide (H2O2) and ascorbic acid (AA), the limits of detection (LODs) were as low as 9.97 μM and 0.039 μM, respectively. The current work highlights a facile and powerful strategy for manufacturing nanozymes with high specific activity and demonstrates that the prepared PtRh HNRs have the potential for analysis and determination.
摘要：
具有高比活性的纳米酶的制备对于各种应用非常重要。然而,只有少数纳米酶具有与天然酶相当的特定活性。在这里，开发了新型Pt-on-Rh中空纳米棒（PtRhHNRs），其中表面Pt表现出可调节的分散性，内部Rh用作载体。优化的PtRhHNRs表现出高性能过氧化物酶（POD）样活性，比活度高达1352Umg-1，是单金属Pt对应物的3.86倍。密度泛函理论（DFT）计算表明，Rh的存在降低了速率决定步骤的能垒。当PtRhHNRs用作纳米酶在过氧化氢（H2O2）和抗坏血酸（AA）的比色检测中，检测限（LOD）低至9.97μM和0.039μM，分别。目前的工作强调了制造具有高比活性的纳米酶的简单而强大的策略，并证明了制备的PtRhHNRs具有分析和测定的潜力。
