PDF(Pubmed)
Abstract：
(1) Background: Mental disorders are conditions that affect a person\'s cognition, mood, and behaviour, such as depression, anxiety, bipolar disorder, and schizophrenia. In contrast, neurological disorders are diseases of the brain, spinal cord, and nerves. Such disorders include strokes, epilepsy, Alzheimer\'s, and Parkinson\'s. Both mental and neurological disorders pose significant global health challenges, impacting hundreds of millions worldwide. Research suggests that certain vitamins, including vitamin D, may influence the incidence and severity of these disorders; (2) Methods: This systematic review examined the potential effects of vitamin D supplementation on various mental and neurological disorders. Evidence was gathered from databases like PubMed, Cochrane, and Google Scholar, including multiple randomized controlled trials comparing vitamin D supplementation to placebo or no treatment for conditions like depression, bipolar disorder, epilepsy, schizophrenia, and neuroinflammation; (3) Results: The findings strongly indicate that vitamin D supplementation may benefit a range of mental health and neurological disorders. The magnitude of the beneficial impact varied by specific disorder, but the overall pattern strongly supports the therapeutic potential of vitamin D on these disorders; (4) Conclusions: This review provides valuable insight into the role vitamin D may play in the management of critical brain-related health issues.
摘要：
(1)背景：精神障碍是影响一个人的认知的条件，心情,和行为，比如抑郁症，焦虑,双相情感障碍,和精神分裂症。相比之下,神经系统疾病是大脑的疾病，脊髓,和神经。这些疾病包括中风，癫痫,老年痴呆症,和帕金森。精神和神经系统疾病都构成了重大的全球健康挑战。影响全球数亿人。研究表明某些维生素,包括维生素D,可能会影响这些疾病的发病率和严重程度；（2）方法：本系统评价了补充维生素D对各种精神和神经系统疾病的潜在影响。证据是从PubMed这样的数据库收集的,科克伦,和谷歌学者，包括多项随机对照试验，将补充维生素D与安慰剂或不治疗抑郁症等疾病进行比较，双相情感障碍,癫痫,精神分裂症,（3）结果：发现强烈表明补充维生素D可能有益于一系列心理健康和神经系统疾病。有益影响的程度因特定疾病而异，但总体模式强烈支持维生素D对这些疾病的治疗潜力;(4)结论:这篇综述提供了对维生素D在关键脑相关健康问题管理中可能发挥的作用的有价值的见解。
