关键词: Aral Sea region Cancer morbidity heavy metals

Mesh : Humans Kazakhstan / epidemiology Metals, Heavy / analysis Incidence Soil Pollutants / analysis Neoplasms / epidemiology Soil / chemistry Male Female Prognosis Follow-Up Studies

来  源:   DOI:10.31557/APJCP.2024.25.6.1987

Abstract:
OBJECTIVE: The purpose of this study was to investigate the relationship of soil pollution factors such as heavy metal ions with the incidence of cancer in the Kyzylorda region of Kazakhstan.
METHODS: Concentrations of heavy metal ions in the soils of different sites of Kyzylorda region, Kazakhstan, were sampled and correlated with incidence of cancer in 2021.
RESULTS: Chromium content in the soil exceeded maximum permissible concentration (MPC) in the samples for all sites except Kazaly and Shieli, and the highest excess of 2.8 MPC was found in Terenozek. Content of copper, lead, and cobalt ions was also increased and varied in the range 1.9-15.4, 1.2-4, and 1.2-2.44 MPC, respectively. In addition, lung cancer incidence was statistically significantly correlated with soil concentration to MPC ratio of copper, cobalt, and lead; colorectal cancer was correlated with soil concentration of chromium. Cases of invasive cancer and mutations were recorded Terenozek and Kyzylorda areas.
CONCLUSIONS: The higher the soil concentration correlate with higher cancer incidence in Kyzylorda region, Kazakhstan.
摘要:
目的:本研究的目的是调查哈萨克斯坦Kyzylorda地区重金属离子等土壤污染因素与癌症发病率的关系。
方法:Kyzylorda地区不同地点土壤中重金属离子的浓度,哈萨克斯坦,进行了采样,并与2021年的癌症发病率相关。
结果:除Kazaly和Shieli以外的所有地点,土壤中的铬含量超过了样品中的最大允许浓度(MPC),在Terenozek发现最高的超过2.8MPC。铜含量,铅,钴离子也在1.9-15.4、1.2-4和1.2-2.44MPC范围内增加和变化,分别。此外,肺癌发病率与土壤浓度与铜的MPC比值有统计学显著相关,钴,和铅;结直肠癌与土壤铬浓度相关。浸润性癌症和突变的病例记录在Terenozek和Kyzylorda区域。
结论:在Kyzylorda地区,土壤浓度越高,癌症发病率越高,哈萨克斯坦。
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