PDF(Pubmed)
Abstract：
Visual assessment, while the primary method for pigmentation and erythema evaluation in clinical practice, is subjective, time-consuming, and may lead to variability in observations among clinicians. Objective and quantitative techniques are required for a precise evaluation of the disease\'s severity and the treatment\'s efficacy. This research examines the precision and utility of a newly developed skin imaging system in assessing pigmentation and erythema. Sixty participants were recruited, and their facial images were analyzed with the new OBSERV 520 x skin imaging system, compared to DERMACATCH for regional analysis and VISIA for full-face examination. The degree of skin pigmentation was clinically graded using the MASI scores evaluated by dermatologists. The data revealed positive correlations between the novel skin imaging system and the two conventional instruments in quantifying pigmentation and erythema, whether in regional or full-face analysis. Furthermore, the new skin imaging system positively correlated with the clinical MASI scores (r = 0.4314, P < 0.01). In contrast, our study found no significant correlation between the traditional system and clinical assessment, indicating a more substantial capacity for hyperpigmentation assessment in the new system. Our study validates the innovative skin imaging system\'s accuracy in evaluating pigmentation and erythema, demonstrating its feasibility for quantitative evaluation in both clinical and research purposes.
摘要：
视觉评估，而在临床实践中，色素沉着和红斑的主要评估方法，是主观的，耗时,并可能导致临床医生之间的观察差异。需要客观和定量技术来精确评估疾病的严重程度和治疗效果。这项研究检查了新开发的皮肤成像系统在评估色素沉着和红斑方面的准确性和实用性。招募了60名参与者，他们的面部图像用新的OBSERV520x皮肤成像系统分析，与DERMACATCH进行区域分析和VISIA进行全面检查相比。使用皮肤科医生评估的MASI评分对皮肤色素沉着的程度进行临床分级。数据显示，新型皮肤成像系统与两种常规仪器在定量色素沉着和红斑方面呈正相关。无论是区域分析还是全面分析。此外，新的皮肤成像系统与临床MASI评分呈正相关(r=0.4314,P<0.01)。相比之下,我们的研究发现传统系统和临床评估之间没有显着相关性，表明在新系统中更有能力评估色素沉着过度。我们的研究验证了创新的皮肤成像系统在评估色素沉着和红斑方面的准确性，证明其在临床和研究目的的定量评估的可行性。
