Abstract：
OBJECTIVE: Before June 2022, the treatment cost of Burkitt lymphoma (BL) in Ghana was mainly borne by the child\'s family or caregiver. We determined the treatment cost of BL in children and its psychological impact on parents and caregivers.
METHODS: This prospective observational study assessed the direct medical and nonmedical costs (US dollars [USD]) incurred during the treatment of a child with BL for 6 consecutive months using a cost diary. Productivity losses and the psychological impact on parents and caregivers were assessed using a self-administered questionnaire and the Caregiver Quality of Life Index-Cancer (CQOLC).
RESULTS: Of the 25 participants, 7 abandoned the treatment of their children, and 4 withdrew because the children passed away. The median (Q1, Q3) cost for treating BL per child for caregivers/parents (N = 12) was USD 947.42 (USD 763.03, USD 1953.05). Direct medical costs formed 71% (USD 11 458.97) of total treatment costs. Working hours of parents before the child\'s cancer diagnosis decreased from a median (Q1, Q3) of 44.00 (20.00, 66.00) hours to 1.50 (0, 20.00) hours after the diagnosis. The mean (SD) CQOLC score was 107.92 (15.89), with higher scores in men (111.00 [17.26]), married participants (111.26 [17.29]), Higher National Diploma certificate holders (113.00 [1.41]), and participants earning a monthly income more than USD 84.60.
CONCLUSIONS: Treatment costs reduced the overall household income of 5 families. Parents and caregivers experienced reduced work hours and loss of employment. CQOLC scores were higher in married participants, those with a higher educational background, and those with higher income.
METHODS: This prospective observational study assessed the direct medical and nonmedical costs (US dollars [USD]) incurred during the treatment of a child with BL for 6 consecutive months using a cost diary. Productivity losses and the psychological impact on parents and caregivers were assessed using a self-administered questionnaire and the Caregiver Quality of Life Index-Cancer (CQOLC).
RESULTS: Of the 25 participants, 7 abandoned the treatment of their children, and 4 withdrew because the children passed away. The median (Q1, Q3) cost for treating BL per child for caregivers/parents (N = 12) was USD 947.42 (USD 763.03, USD 1953.05). Direct medical costs formed 71% (USD 11 458.97) of total treatment costs. Working hours of parents before the child\'s cancer diagnosis decreased from a median (Q1, Q3) of 44.00 (20.00, 66.00) hours to 1.50 (0, 20.00) hours after the diagnosis. The mean (SD) CQOLC score was 107.92 (15.89), with higher scores in men (111.00 [17.26]), married participants (111.26 [17.29]), Higher National Diploma certificate holders (113.00 [1.41]), and participants earning a monthly income more than USD 84.60.
CONCLUSIONS: Treatment costs reduced the overall household income of 5 families. Parents and caregivers experienced reduced work hours and loss of employment. CQOLC scores were higher in married participants, those with a higher educational background, and those with higher income.
摘要：
目的：在2022年6月之前，加纳伯基特淋巴瘤（BL）的治疗费用主要由儿童的家人或照顾者承担。我们确定了儿童BL的治疗费用及其对父母和照顾者的心理影响。
方法：这项前瞻性观察性研究使用费用日记评估了连续6个月治疗儿童BL期间发生的直接医疗和非医疗费用（美元[USD]）。使用自我管理问卷和照顾者生活质量指数癌症（CQOLC）评估生产力损失以及对父母和照顾者的心理影响。
结果：在25名参与者中，7放弃了对孩子的待遇，4因为孩子们过世而退出。照顾者/父母(N=12)每个孩子治疗BL的中位数(Q1,Q3)成本为947.42美元(763.03美元,1953.05美元)。直接医疗费用占总治疗费用的71%(11458.97美元)。父母在儿童癌症诊断前的工作时间从中位数（Q1，Q3）44.00（20.00，66.00）小时减少到诊断后1.50（0，20.00）小时。平均（SD）CQOLC评分为107.92（15.89），男性得分较高(111.00[17.26])，已婚参与者(111.26[17.29])，国家高级文凭证书持有人（113.00[1.41]），参与者的月收入超过84.60美元。
结论：治疗费用降低了5个家庭的整体家庭收入。父母和照顾者的工作时间减少和失业。CQOLC在已婚参与者中得分较高，那些受过高等教育的人，以及收入较高的人。
方法：这项前瞻性观察性研究使用费用日记评估了连续6个月治疗儿童BL期间发生的直接医疗和非医疗费用（美元[USD]）。使用自我管理问卷和照顾者生活质量指数癌症（CQOLC）评估生产力损失以及对父母和照顾者的心理影响。
结果：在25名参与者中，7放弃了对孩子的待遇，4因为孩子们过世而退出。照顾者/父母(N=12)每个孩子治疗BL的中位数(Q1,Q3)成本为947.42美元(763.03美元,1953.05美元)。直接医疗费用占总治疗费用的71%(11458.97美元)。父母在儿童癌症诊断前的工作时间从中位数（Q1，Q3）44.00（20.00，66.00）小时减少到诊断后1.50（0，20.00）小时。平均（SD）CQOLC评分为107.92（15.89），男性得分较高(111.00[17.26])，已婚参与者(111.26[17.29])，国家高级文凭证书持有人（113.00[1.41]），参与者的月收入超过84.60美元。
结论：治疗费用降低了5个家庭的整体家庭收入。父母和照顾者的工作时间减少和失业。CQOLC在已婚参与者中得分较高，那些受过高等教育的人，以及收入较高的人。
