METHODS: This prospective observational study assessed the direct medical and nonmedical costs (US dollars [USD]) incurred during the treatment of a child with BL for 6 consecutive months using a cost diary. Productivity losses and the psychological impact on parents and caregivers were assessed using a self-administered questionnaire and the Caregiver Quality of Life Index-Cancer (CQOLC).
RESULTS: Of the 25 participants, 7 abandoned the treatment of their children, and 4 withdrew because the children passed away. The median (Q1, Q3) cost for treating BL per child for caregivers/parents (N = 12) was USD 947.42 (USD 763.03, USD 1953.05). Direct medical costs formed 71% (USD 11 458.97) of total treatment costs. Working hours of parents before the child\'s cancer diagnosis decreased from a median (Q1, Q3) of 44.00 (20.00, 66.00) hours to 1.50 (0, 20.00) hours after the diagnosis. The mean (SD) CQOLC score was 107.92 (15.89), with higher scores in men (111.00 [17.26]), married participants (111.26 [17.29]), Higher National Diploma certificate holders (113.00 [1.41]), and participants earning a monthly income more than USD 84.60.
CONCLUSIONS: Treatment costs reduced the overall household income of 5 families. Parents and caregivers experienced reduced work hours and loss of employment. CQOLC scores were higher in married participants, those with a higher educational background, and those with higher income.
方法:这项前瞻性观察性研究使用费用日记评估了连续6个月治疗儿童BL期间发生的直接医疗和非医疗费用(美元[USD])。使用自我管理问卷和照顾者生活质量指数癌症(CQOLC)评估生产力损失以及对父母和照顾者的心理影响。
结果:在25名参与者中,7放弃了对孩子的待遇,4因为孩子们过世而退出。照顾者/父母(N=12)每个孩子治疗BL的中位数(Q1,Q3)成本为947.42美元(763.03美元,1953.05美元)。直接医疗费用占总治疗费用的71%(11458.97美元)。父母在儿童癌症诊断前的工作时间从中位数(Q1,Q3)44.00(20.00,66.00)小时减少到诊断后1.50(0,20.00)小时。平均(SD)CQOLC评分为107.92(15.89),男性得分较高(111.00[17.26]),已婚参与者(111.26[17.29]),国家高级文凭证书持有人(113.00[1.41]),参与者的月收入超过84.60美元。
结论:治疗费用降低了5个家庭的整体家庭收入。父母和照顾者的工作时间减少和失业。CQOLC在已婚参与者中得分较高,那些受过高等教育的人,以及收入较高的人。