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Abstract：
BACKGROUND: We sought to determine the effectiveness and utility of two-dimensional shear-wave sonoelastography (2D-SW-SE) in the diagnosis and postoperative follow-up of infantile hypertrophic pyloric stenosis (IHPS).
METHODS: Twenty-three infants were included in the study, 13 in the IHPS group and 10 in the control group (CG). Preoperative B-mode ultrasonography measurements (longitudinal length and single-wall thickness of the pylorus) and 2D-SW-SE measurements (pylorus tissue stiffness and shear-wave propagation speed) were compared between the groups. The infants with IHPS then underwent Ramstedt pyloromyotomy and were invited for follow-ups on the tenth day and the first, third, and sixth months postoperatively. Measurements taken at the follow-ups were compared with the preoperative values.
RESULTS: No differences were found between the groups regarding age, gender, body weight, or week of birth. The pyloric lengths in the IHPS group were longer than in the CG (p < 0.001), and the single-wall thicknesses were thicker (p < 0.001). The pylorus in the IHPS group was four times stiffer than in the CG (27.4 kPa versus 7.66 kPa), and the shear-wave propagation speed in the tissue was higher (1.34 m/s versus 2.69 m/s; p < 0.001). Both values decreased over time in the IHPS group and were normal by the third postoperative month.
CONCLUSIONS: 2D-SW-SE can be used as an assistive imaging tool alongside B-mode ultrasound for diagnosing IHPS. It can also be used to identify inadequate surgery by detecting whether the pyloric tissue has softened at follow-up.
METHODS: Twenty-three infants were included in the study, 13 in the IHPS group and 10 in the control group (CG). Preoperative B-mode ultrasonography measurements (longitudinal length and single-wall thickness of the pylorus) and 2D-SW-SE measurements (pylorus tissue stiffness and shear-wave propagation speed) were compared between the groups. The infants with IHPS then underwent Ramstedt pyloromyotomy and were invited for follow-ups on the tenth day and the first, third, and sixth months postoperatively. Measurements taken at the follow-ups were compared with the preoperative values.
RESULTS: No differences were found between the groups regarding age, gender, body weight, or week of birth. The pyloric lengths in the IHPS group were longer than in the CG (p < 0.001), and the single-wall thicknesses were thicker (p < 0.001). The pylorus in the IHPS group was four times stiffer than in the CG (27.4 kPa versus 7.66 kPa), and the shear-wave propagation speed in the tissue was higher (1.34 m/s versus 2.69 m/s; p < 0.001). Both values decreased over time in the IHPS group and were normal by the third postoperative month.
CONCLUSIONS: 2D-SW-SE can be used as an assistive imaging tool alongside B-mode ultrasound for diagnosing IHPS. It can also be used to identify inadequate surgery by detecting whether the pyloric tissue has softened at follow-up.
摘要：
背景：我们试图确定二维剪切波超声弹性成像（2D-SW-SE）在婴儿肥厚性幽门狭窄（IHPS）的诊断和术后随访中的有效性和实用性。
方法：23名婴儿被纳入研究，IHPS组中的13和对照组(CG)中的10。比较两组之间的术前B型超声检查测量值（幽门的纵向长度和单壁厚度）和2D-SW-SE测量值（幽门组织刚度和剪切波传播速度）。然后，患有IHPS的婴儿接受了Ramstedt幽门切开术，并在第10天和第1天被邀请进行随访，第三,术后6个月。将随访时的测量值与术前值进行比较。
结果：两组在年龄方面没有发现差异，性别,体重,或出生的一周。IHPS组的幽门长度长于CG（p<0.001），单壁厚度较厚(p<0.001)。IHPS组的幽门是CG的四倍（27.4kPa对7.66kPa），剪切波在组织中的传播速度更高（1.34m/s对2.69m/s；p<0.001）。IHPS组的两个值都随着时间的推移而下降，并且在术后第三个月均正常。
结论：2D-SW-SE可作为B型超声辅助成像工具用于诊断IHPS。它还可以用于通过检测幽门组织是否在随访时软化来识别不适当的手术。
方法：23名婴儿被纳入研究，IHPS组中的13和对照组(CG)中的10。比较两组之间的术前B型超声检查测量值（幽门的纵向长度和单壁厚度）和2D-SW-SE测量值（幽门组织刚度和剪切波传播速度）。然后，患有IHPS的婴儿接受了Ramstedt幽门切开术，并在第10天和第1天被邀请进行随访，第三,术后6个月。将随访时的测量值与术前值进行比较。
结果：两组在年龄方面没有发现差异，性别,体重,或出生的一周。IHPS组的幽门长度长于CG（p<0.001），单壁厚度较厚(p<0.001)。IHPS组的幽门是CG的四倍（27.4kPa对7.66kPa），剪切波在组织中的传播速度更高（1.34m/s对2.69m/s；p<0.001）。IHPS组的两个值都随着时间的推移而下降，并且在术后第三个月均正常。
结论：2D-SW-SE可作为B型超声辅助成像工具用于诊断IHPS。它还可以用于通过检测幽门组织是否在随访时软化来识别不适当的手术。
