Abstract：
UNASSIGNED: Polymer nanogels are among the most promising nanoplatforms for use in biomedical applications. The substantial interest for these drug carriers is to enhance the transportation of bioactive substances, reduce the side effects, and achieve optimal action on the curative sites by targeting delivery and triggering the release of the drugs in a controlled and continuous mode.
UNASSIGNED: The review discusses the opportunities, applications, and challenges of synthetic polypeptide nanogels in biomedicine, with an emphasis on the recent progress in cancer therapy. It is evidenced by the development of polypeptide nanogels for better controlled drug delivery and release, in complex in vivo microenvironments in biomedical applications.
UNASSIGNED: Polypeptide nanogels can be developed by choosing the amino acids from the peptide structure that are suitable for the type of application. Using a stimulus - sensitive peptide nanogel, it is possible to obtain the appropriate transport and release of the drug, as well as to achieve desirable therapeutic effects, including safety, specificity, and efficiency. The final system represents an innovative way for local and sustained drug delivery at a specific site of the body.
UNASSIGNED: The review discusses the opportunities, applications, and challenges of synthetic polypeptide nanogels in biomedicine, with an emphasis on the recent progress in cancer therapy. It is evidenced by the development of polypeptide nanogels for better controlled drug delivery and release, in complex in vivo microenvironments in biomedical applications.
UNASSIGNED: Polypeptide nanogels can be developed by choosing the amino acids from the peptide structure that are suitable for the type of application. Using a stimulus - sensitive peptide nanogel, it is possible to obtain the appropriate transport and release of the drug, as well as to achieve desirable therapeutic effects, including safety, specificity, and efficiency. The final system represents an innovative way for local and sustained drug delivery at a specific site of the body.
摘要：
聚合物纳米凝胶是用于生物医学应用的最有前途的纳米平台之一。这些药物载体的实质兴趣是增强生物活性物质的运输，减少副作用，并通过靶向递送和以受控和连续模式触发药物的释放来实现对治疗部位的最佳作用。
■评论讨论了机会，应用程序,以及生物医学中合成多肽纳米凝胶的挑战，重点介绍了癌症治疗的最新进展。多肽纳米凝胶的发展可以更好地控制药物的递送和释放，在生物医学应用中复杂的体内微环境中。
■可以通过从肽结构中选择适合应用类型的氨基酸来开发多肽纳米凝胶。使用刺激敏感肽纳米凝胶，有可能获得药物的适当运输和释放，以及达到理想的治疗效果，包括安全,特异性，和效率。最终系统代表了在身体的特定部位进行局部和持续药物递送的创新方式。
■评论讨论了机会，应用程序,以及生物医学中合成多肽纳米凝胶的挑战，重点介绍了癌症治疗的最新进展。多肽纳米凝胶的发展可以更好地控制药物的递送和释放，在生物医学应用中复杂的体内微环境中。
■可以通过从肽结构中选择适合应用类型的氨基酸来开发多肽纳米凝胶。使用刺激敏感肽纳米凝胶，有可能获得药物的适当运输和释放，以及达到理想的治疗效果，包括安全,特异性，和效率。最终系统代表了在身体的特定部位进行局部和持续药物递送的创新方式。
