PDF(Pubmed)
Abstract：
UNASSIGNED: Beta-lactam antibiotics are first-line agents for most patients receiving antimicrobial prophylaxis in surgical procedures. Despite evidence showing low cross-reactivity between penicillins and cephalosporins, patients with beta-lactam allergies commonly receive vancomycin as an alternative to avoid allergic reaction.
UNASSIGNED: Adult patients receiving vancomycin for surgical prophylaxis with a reported beta-lactam allergy at our institution between August 2017 to July 2018 were retrospectively evaluated for potential eligibility for penicillin allergy testing and/or receipt of standard prophylaxis.
UNASSIGNED: Among 830 patients who received vancomycin for surgical prophylaxis, 196 reported beta-lactam allergy and were included in the analysis. Approximately 40 % of surgeries were orthopedic. Of patients receiving vancomycin as first-line therapy, 189 (96.4 %) were potentially eligible for beta-lactam prophylaxis.
UNASSIGNED: Patients with beta-lactam allergies often qualify for receipt of a first-line antibiotic. An opportunity exists for improved allergy assessment as an antimicrobial stewardship intervention in surgical prophylaxis.
UNASSIGNED: Adult patients receiving vancomycin for surgical prophylaxis with a reported beta-lactam allergy at our institution between August 2017 to July 2018 were retrospectively evaluated for potential eligibility for penicillin allergy testing and/or receipt of standard prophylaxis.
UNASSIGNED: Among 830 patients who received vancomycin for surgical prophylaxis, 196 reported beta-lactam allergy and were included in the analysis. Approximately 40 % of surgeries were orthopedic. Of patients receiving vancomycin as first-line therapy, 189 (96.4 %) were potentially eligible for beta-lactam prophylaxis.
UNASSIGNED: Patients with beta-lactam allergies often qualify for receipt of a first-line antibiotic. An opportunity exists for improved allergy assessment as an antimicrobial stewardship intervention in surgical prophylaxis.
摘要：
β-内酰胺类抗生素是大多数在外科手术中接受抗菌预防的患者的一线药物。尽管有证据表明青霉素和头孢菌素之间的交叉反应性低，β-内酰胺类过敏患者通常接受万古霉素治疗以避免过敏反应.
在2017年8月至2018年7月期间在我们机构接受万古霉素手术预防并报告β-内酰胺过敏的成年患者接受青霉素过敏测试和/或接受标准预防的潜在资格进行回顾性评估。
■在接受万古霉素手术预防的830名患者中，196报告了β-内酰胺过敏，并包括在分析中。大约40%的手术是骨科手术。在接受万古霉素作为一线治疗的患者中，189人（96.4%）可能符合β-内酰胺预防的条件。
β-内酰胺过敏患者通常有资格获得一线抗生素。作为手术预防中的抗菌管理干预措施，存在改善过敏评估的机会。
在2017年8月至2018年7月期间在我们机构接受万古霉素手术预防并报告β-内酰胺过敏的成年患者接受青霉素过敏测试和/或接受标准预防的潜在资格进行回顾性评估。
■在接受万古霉素手术预防的830名患者中，196报告了β-内酰胺过敏，并包括在分析中。大约40%的手术是骨科手术。在接受万古霉素作为一线治疗的患者中，189人（96.4%）可能符合β-内酰胺预防的条件。
β-内酰胺过敏患者通常有资格获得一线抗生素。作为手术预防中的抗菌管理干预措施，存在改善过敏评估的机会。
