{Reference Type}: Journal Article
{Title}: Utility of beta-lactam allergy assessment in patients receiving vancomycin for surgical prophylaxis.
{Author}: Tucker KJ;Ham Y;Holmer HK;McCracken CM;Sukerman E;Lewis JS;McGregor JC;
{Journal}: Surg Pract Sci
{Volume}: 16
{Issue}: 0
{Year}: 2024 Mar
暂无{DOI}: 10.1016/j.sipas.2023.100232
{Abstract}: <B>UNASSIGNED: </B>Beta-lactam antibiotics are first-line agents for most patients receiving antimicrobial prophylaxis in surgical procedures. Despite evidence showing low cross-reactivity between penicillins and cephalosporins, patients with beta-lactam allergies commonly receive vancomycin as an alternative to avoid allergic reaction.<BR><B>UNASSIGNED: </B>Adult patients receiving vancomycin for surgical prophylaxis with a reported beta-lactam allergy at our institution between August 2017 to July 2018 were retrospectively evaluated for potential eligibility for penicillin allergy testing and/or receipt of standard prophylaxis.<BR><B>UNASSIGNED: </B>Among 830 patients who received vancomycin for surgical prophylaxis, 196 reported beta-lactam allergy and were included in the analysis. Approximately 40 % of surgeries were orthopedic. Of patients receiving vancomycin as first-line therapy, 189 (96.4 %) were potentially eligible for beta-lactam prophylaxis.<BR><B>UNASSIGNED: </B>Patients with beta-lactam allergies often qualify for receipt of a first-line antibiotic. An opportunity exists for improved allergy assessment as an antimicrobial stewardship intervention in surgical prophylaxis.