PDF(Pubmed)
Abstract：
UNASSIGNED: The presence of the Penicillium section Aspergilloides (formerly known as Penicillium glabrum) in the cork industry involves the risk of respiratory diseases such as suberosis.
UNASSIGNED: The aim of this study was to corroborate the predominant fungi present in this occupational environment by performing a mycological analysis of 360 workers\' nasal exudates collected by nasal swabs. Additionally, evaluation of respiratory disorders among the cork workers was also performed by spirometry.
UNASSIGNED: Penicillium section Aspergilloides was detected by qPCR in 37 out of the 360 nasal swabs collected from workers\' samples. From those, 25 remained negative for Penicillium sp. when using culture-based methods. A significant association was found between ventilatory defects and years of work in the cork industry, with those people working for 10 or more years in this industry having an approximately two-fold increased risk of having ventilatory defects compared to those working less time in this setting. Among the workers who detected the presence of Penicillium section Aspergilloides, those with symptoms presented slightly higher average values of CFU.
UNASSIGNED: Overall, the results obtained in this study show that working in the cork industry may have adverse effects on worker\'s respiratory health. Nevertheless, more studies are needed (e.g., using serological assays) to clarify the impact of each risk factor (fungi and dust) on disease etiology.
UNASSIGNED: The aim of this study was to corroborate the predominant fungi present in this occupational environment by performing a mycological analysis of 360 workers\' nasal exudates collected by nasal swabs. Additionally, evaluation of respiratory disorders among the cork workers was also performed by spirometry.
UNASSIGNED: Penicillium section Aspergilloides was detected by qPCR in 37 out of the 360 nasal swabs collected from workers\' samples. From those, 25 remained negative for Penicillium sp. when using culture-based methods. A significant association was found between ventilatory defects and years of work in the cork industry, with those people working for 10 or more years in this industry having an approximately two-fold increased risk of having ventilatory defects compared to those working less time in this setting. Among the workers who detected the presence of Penicillium section Aspergilloides, those with symptoms presented slightly higher average values of CFU.
UNASSIGNED: Overall, the results obtained in this study show that working in the cork industry may have adverse effects on worker\'s respiratory health. Nevertheless, more studies are needed (e.g., using serological assays) to clarify the impact of each risk factor (fungi and dust) on disease etiology.
摘要：
■在软木行业中存在青霉部分Aspergilloides（以前称为glabrum青霉）涉及呼吸道疾病的风险，例如亚黄病。
■这项研究的目的是通过对鼻拭子收集的360名工人的鼻分泌物进行真菌学分析来证实这种职业环境中存在的主要真菌。此外,还通过肺活量测定法对软木工人的呼吸系统疾病进行了评估。
■青霉切片通过qPCR在从工人\'样本中收集的360个鼻拭子中的37个中检测到了曲霉属。从那些,25对青霉菌属保持阴性。使用基于文化的方法时。发现通气缺陷与软木行业的多年工作之间存在显着关联，与那些在这个行业工作了10年或更长时间的人相比，在这个行业工作了10年或更长时间的人患通气缺陷的风险增加了大约两倍。在检测到存在青霉部分的工人中，有症状的患者的CFU平均值略高.
■总的来说，这项研究的结果表明，在软木行业工作可能会对工人的呼吸健康产生不利影响。然而，需要更多的研究(例如，使用血清学测定）来阐明每个风险因素（真菌和灰尘）对疾病病因的影响。
■这项研究的目的是通过对鼻拭子收集的360名工人的鼻分泌物进行真菌学分析来证实这种职业环境中存在的主要真菌。此外,还通过肺活量测定法对软木工人的呼吸系统疾病进行了评估。
■青霉切片通过qPCR在从工人\'样本中收集的360个鼻拭子中的37个中检测到了曲霉属。从那些,25对青霉菌属保持阴性。使用基于文化的方法时。发现通气缺陷与软木行业的多年工作之间存在显着关联，与那些在这个行业工作了10年或更长时间的人相比，在这个行业工作了10年或更长时间的人患通气缺陷的风险增加了大约两倍。在检测到存在青霉部分的工人中，有症状的患者的CFU平均值略高.
■总的来说，这项研究的结果表明，在软木行业工作可能会对工人的呼吸健康产生不利影响。然而，需要更多的研究(例如，使用血清学测定）来阐明每个风险因素（真菌和灰尘）对疾病病因的影响。
