表征,结构,和抑制人琥珀酰辅酶 A : 戊二酸辅酶 A 转移酶 ,戊二酸 1 型的推定遗传修饰剂。
Mesh : Humans Amino Acid Metabolism, Inborn Errors / drug therapy metabolism enzymology genetics Brain Diseases, Metabolic / drug therapy metabolism enzymology Glutarates / metabolism chemistry Losartan / pharmacology chemistry Coenzyme A-Transferases / metabolism antagonists & inhibitors genetics chemistry Valsartan Enzyme Inhibitors / pharmacology chemistry Crystallography, X-Ray Catalytic Domain Acyl Coenzyme A / metabolism chemistry Models, Molecular High-Throughput Screening Assays Glutaryl-CoA Dehydrogenase / deficiency
来 源:
DOI:10.1021/acschembio.4c00204
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