Abstract：
OBJECTIVE: Epistaxis is a common condition that affects about 60% of the population in their lifetime, with 6% needing medical attention. Little is known about the epidemiology and risk factors of epistaxis outside the health care system. This study aimed to investigate the prevalence and risk factors of epistaxis in a rural Danish population using data from the Lolland-Falster Health Study (LOFUS).
METHODS: We conducted a cross-sectional survey based on data from LOFUS, a household-based, prospective cohort study in the rural provincial area of Lolland-Falster, Denmark. We enrolled 10,065 participants (≥ 50 years) and collected data on demographics, comorbidities, medication, lifestyle factors, and laboratory parameters. Logistic regressions were used to test for correlations between epistaxis and different risk factors.
RESULTS: In total 5.3% of the participants had experienced epistaxis within the past 30 days, and 7.9% had sought medical attention for epistaxis at some point in their lives. We identified several factors that were significantly correlated with increased odds of epistaxis, such as male gender, age group 50-59 years, high BMI (> 25), allergy, diabetes, hypertension, atherosclerosis, angina, and anticoagulant treatment. Excellent or good self-reported health was correlated to significantly lower odds of epistaxis.
CONCLUSIONS: This study provides a comprehensive overview of the prevalence and risk factors of epistaxis outside the health care system. Our study suggests that preventive measures targeting these risk factors may reduce the incidence and severity of epistaxis in this population.
METHODS: We conducted a cross-sectional survey based on data from LOFUS, a household-based, prospective cohort study in the rural provincial area of Lolland-Falster, Denmark. We enrolled 10,065 participants (≥ 50 years) and collected data on demographics, comorbidities, medication, lifestyle factors, and laboratory parameters. Logistic regressions were used to test for correlations between epistaxis and different risk factors.
RESULTS: In total 5.3% of the participants had experienced epistaxis within the past 30 days, and 7.9% had sought medical attention for epistaxis at some point in their lives. We identified several factors that were significantly correlated with increased odds of epistaxis, such as male gender, age group 50-59 years, high BMI (> 25), allergy, diabetes, hypertension, atherosclerosis, angina, and anticoagulant treatment. Excellent or good self-reported health was correlated to significantly lower odds of epistaxis.
CONCLUSIONS: This study provides a comprehensive overview of the prevalence and risk factors of epistaxis outside the health care system. Our study suggests that preventive measures targeting these risk factors may reduce the incidence and severity of epistaxis in this population.
摘要：
目的：鼻出血是一种常见的疾病，在其一生中会影响约60％的人口，6%的人需要医疗护理。对卫生保健系统外鼻出血的流行病学和危险因素知之甚少。这项研究旨在使用Lolland-Falster健康研究（LOFUS）的数据调查丹麦农村人口鼻出血的患病率和危险因素。
方法：我们根据LOFUS的数据进行了横断面调查，以家庭为基础的，Lolland-Falster农村地区的前瞻性队列研究，丹麦。我们招募了10065名参与者(≥50岁)，并收集了人口统计数据，合并症,药物,生活方式因素，和实验室参数。采用Logistic回归检验鼻出血与不同危险因素的相关性。
结果：总共有5.3%的参与者在过去30天内出现鼻出血，7.9%的人在生命中的某个时候曾因鼻出血寻求医疗护理。我们确定了几个与鼻出血几率增加显著相关的因素，比如男性,年龄组50-59岁，高BMI（>25），过敏,糖尿病,高血压,动脉粥样硬化,心绞痛,抗凝治疗。良好或良好的自我报告的健康状况与鼻出血的几率显着降低相关。
结论：本研究全面概述了卫生保健系统以外鼻出血的患病率和危险因素。我们的研究表明，针对这些危险因素的预防措施可能会降低该人群鼻出血的发生率和严重程度。
方法：我们根据LOFUS的数据进行了横断面调查，以家庭为基础的，Lolland-Falster农村地区的前瞻性队列研究，丹麦。我们招募了10065名参与者(≥50岁)，并收集了人口统计数据，合并症,药物,生活方式因素，和实验室参数。采用Logistic回归检验鼻出血与不同危险因素的相关性。
结果：总共有5.3%的参与者在过去30天内出现鼻出血，7.9%的人在生命中的某个时候曾因鼻出血寻求医疗护理。我们确定了几个与鼻出血几率增加显著相关的因素，比如男性,年龄组50-59岁，高BMI（>25），过敏,糖尿病,高血压,动脉粥样硬化,心绞痛,抗凝治疗。良好或良好的自我报告的健康状况与鼻出血的几率显着降低相关。
结论：本研究全面概述了卫生保健系统以外鼻出血的患病率和危险因素。我们的研究表明，针对这些危险因素的预防措施可能会降低该人群鼻出血的发生率和严重程度。
