Abstract:
Aim of the study was to evaluate the diagnostic performance and feasibility of transabdominal ultrasound shear wave elastography (SWE) in assessing sonoelastographic features of the uterus. Twenty-seven premenopausal women were enrolled between 2021 and 2022. Transabdominal SWE measured myometrial stiffness in various uterine segments. Additionally, tissue stiffness of the quadriceps femoris muscle and autochthonous back muscle was measured. Statistical analysis employed non-parametric tests, t test, and a robust mixed linear model. Stiffness values of the uterus and the two investigated muscle types exhibited a similar spectrum: 6.38 ± 2.59 kPa (median 5.61 kPa; range 2.76-11.31 kPa) for the uterine myometrium, 7.22 ± 1.24 kPa (6.82 kPa; 5.11-9.39 kPa) for the quadriceps femoris musle, and 7.43 ± 2.73 kPa (7.41 kPa; 3.10-13.73 kPa) for the autochthonous back muscle. A tendency for significant differences in myometrial stiffness was observed concerning the type of labor mode (mean stiffness of 9.17 ± 1.35 kPa after vaginal birth vs. 3.83 ± 1.35 kPa after Caesarian section, p = 0.01). No significant differences in myometrial stiffness were observed concerning age, BMI, previous pregnancies, uterine flexion and menstrual cycle phase. Transabdominal SWE of uterine stiffness seems to be a fast and practicable method in a clinical setting. Uterine stiffness appears to be largely independent of various factors, except for the mode of delivery. However, further studies are needed to validate these results.
摘要:
该研究的目的是评估经腹超声剪切波弹性成像(SWE)在评估子宫超声弹性成像特征中的诊断性能和可行性。在2021年至2022年之间招募了27名绝经前妇女。经腹SWE测量了各个子宫段的子宫肌层硬度。此外,测量股四头肌和自体背部肌肉的组织硬度。统计分析采用非参数检验,t测试,和一个鲁棒的混合线性模型。子宫和两种研究的肌肉类型的硬度值表现出相似的频谱:子宫肌层为6.38±2.59kPa(中位数为5.61kPa;范围为2.76-11.31kPa),股四头肌肌7.22±1.24kPa(6.82kPa;5.11-9.39kPa),自体背部肌肉为7.43±2.73kPa(7.41kPa;3.10-13.73kPa)。关于分娩方式的类型,观察到子宫肌层硬度存在显着差异的趋势(阴道分娩后平均硬度为9.17±1.35kPa与剖腹产后3.83±1.35kPa,p=0.01)。关于年龄,未观察到肌层硬度的显着差异,BMI,以前的怀孕,子宫屈曲和月经周期阶段。子宫僵硬的经腹SWE在临床上似乎是一种快速可行的方法。子宫僵硬似乎在很大程度上与各种因素无关,除了交付方式。然而,需要进一步的研究来验证这些结果.