关键词: acute alcoholic hepatitis extrapulmonary legionella legionella infection legionella pneumonia legionella pneumophila new-onset painless jaundice raised liver enzyme transaminitis

来  源:   DOI:10.7759/cureus.60856   PDF(Pubmed)

Abstract:
Legionnaires\' disease is an atypical pneumonia caused by Legionella pneumophila. Legionella species are found in freshwater sources and are transmitted through inhalation of contaminated aerosols. Patients commonly present with fever, chills, and cough. However, in immunosuppressed patients or severe cases, the disease can lead to multiorgan failure. In recent years, the incidence of Legionnaires\' disease has drastically increased and unfortunately is commonly underdiagnosed. Gold-standard diagnosis is made through sputum cultures; however, urine Legionella antigen remains the most common test used for diagnosis. Goal-directed care includes antibiotics and supportive care. This case highlights a rare and unique presentation of Legionnaires\' disease presenting with an elevated 2:1 aspartate aminotransferase to alanine transaminase pattern, typically seen with alcoholic hepatitis.
摘要:
军团菌病是由嗜肺军团菌引起的非典型肺炎。军团菌物种在淡水来源中发现,并通过吸入受污染的气溶胶传播。通常出现发烧的患者,发冷,还有咳嗽.然而,在免疫抑制患者或严重病例中,这种疾病会导致多器官衰竭。近年来,军团病的发病率急剧增加,不幸的是通常诊断不足。金标准诊断是通过痰培养;然而,尿军团菌抗原仍然是最常用的诊断方法。目标导向护理包括抗生素和支持性护理。该病例突出了军团病的罕见和独特表现,表现为2:1天冬氨酸转氨酶升高至丙氨酸转氨酶模式。通常见于酒精性肝炎。
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