[Box: see text].
[方框:见正文]。
设计,1 - 芳基多奈哌齐类似物作为抗阿尔茨海默病药物的合成和生物学评价。
关键词: Alzheimer's disease cholinesterase donepezil analogues neuroprotective activity neurotoxicity
Mesh : Alzheimer Disease / drug therapy metabolism Humans Cholinesterase Inhibitors / pharmacology chemical synthesis chemistry Drug Design Neuroprotective Agents / pharmacology chemical synthesis chemistry Acetylcholinesterase / metabolism Butyrylcholinesterase / metabolism Molecular Docking Simulation Structure-Activity Relationship Piperidines / chemistry pharmacology chemical synthesis Molecular Structure Cell Line, Tumor Hydrogen Peroxide / pharmacology antagonists & inhibitors Indoles
来 源:
DOI:10.4155/fmc-2023-0369
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