Abstract：
Atrioventricular (AV) valve disease is a major burden in our Indian subcontinent, where rheumatic heart disease is still prevalent, when compared to the Western world, where degenerative heart disease is more prevalent. Worldwide, nearly 300,000 valve replacements are done every year but not without complications. These challenges can be multidimensional and multiscalar with the macroscopic and microscopic properties of the native patient tissue interacting with the mechanical and bioprosthetic heart valves and rings. Understanding the complex and variable anatomy of the AV valves is essential to know the exact pathophysiology of the disease and to decide the treatment of choice.
摘要：
房室（AV）瓣膜疾病是我们印度次大陆的主要负担，风湿性心脏病仍然很普遍，与西方世界相比，在退化性心脏病更为普遍的地方。全球,每年进行近30万例瓣膜置换手术，但并非没有并发症。这些挑战可以是多维和多标量的,具有与机械和生物假体心脏瓣膜和环相互作用的天然患者组织的宏观和微观特性。了解AV瓣膜的复杂多变的解剖结构对于了解疾病的确切病理生理学并决定选择的治疗至关重要。
