PDF(Pubmed)
Abstract：
BACKGROUND: Magnetic resonance elastography (MRE) is a rapidly developing medical imaging technique that allows for quantitative assessment of the biomechanical properties of the tissue. MRE is now regarded as the most accurate noninvasive test for detecting and staging liver fibrosis. A two-dimensional (2D MRE) acquisition version is currently deployed at >2000 locations worldwide. 2D MRE allows for the evaluation of the magnitude of the complex shear modulus, also referred to as stiffness. The development of 3D vector MRE has enabled researchers to assess the biomechanical properties of small organs where wave propagation cannot be adequately analyzed with the 2D MRE imaging approach used in the liver. In 3D vector MRE, the shear waves are imaged and processed throughout a 3D volume and processed with an algorithm that accounts for wave propagation in any direction. Additionally, the motion is also imaged in x, y, and z directions at each voxel, allowing for more advanced processing to be applied.
OBJECTIVE: This review describes the technical principles of 3D vector MRE, surveys its clinical applications in small organs, and discusses potential clinical significance of 3D vector MRE.
CONCLUSIONS: 3D vector MRE is a promising tool for characterizing the biomechanical properties of small organs such as the uterus, pancreas, thyroid, prostate, and salivary glands. However, its potential has not yet been fully explored.
OBJECTIVE: This review describes the technical principles of 3D vector MRE, surveys its clinical applications in small organs, and discusses potential clinical significance of 3D vector MRE.
CONCLUSIONS: 3D vector MRE is a promising tool for characterizing the biomechanical properties of small organs such as the uterus, pancreas, thyroid, prostate, and salivary glands. However, its potential has not yet been fully explored.
摘要：
背景：磁共振弹性成像（MRE）是一种快速发展的医学成像技术，可以定量评估组织的生物力学特性。MRE现在被认为是检测和分期肝纤维化的最准确的非侵入性测试。二维（2DMRE）采集版本目前已部署在全球2000多个位置。2DMRE允许评估复数剪切模量的大小，也称为刚度。3D矢量MRE的发展使研究人员能够评估小器官的生物力学特性，其中波传播无法通过肝脏中使用的2DMRE成像方法进行充分分析。在3D矢量MRE中，在整个3D体积中对剪切波进行成像和处理，并使用算法进行处理，该算法考虑了波在任何方向的传播。此外,运动也在x中成像，y,和每个体素的z方向，允许应用更先进的处理。
目的：这篇综述描述了3D矢量MRE的技术原理，调查其在小器官中的临床应用，并讨论了3D载体MRE的潜在临床意义。
结论：3D矢量MRE是表征子宫等小器官生物力学特性的有前途的工具，胰腺,甲状腺，前列腺,和唾液腺.然而,其潜力尚未得到充分挖掘。
目的：这篇综述描述了3D矢量MRE的技术原理，调查其在小器官中的临床应用，并讨论了3D载体MRE的潜在临床意义。
结论：3D矢量MRE是表征子宫等小器官生物力学特性的有前途的工具，胰腺,甲状腺，前列腺,和唾液腺.然而,其潜力尚未得到充分挖掘。
