Abstract：
BACKGROUND: Processing Speed (PS) deficits represent a fundamental aspect of cognitive impairment, evident not only in schizophrenia but also in individuals undergoing their first episode of psychosis (FEP) and their unaffected first-degree relatives. Heterogeneity in tests assessing PS reflects the participation of motor and cognitive subcomponents to varying degrees. We aim to explore differences in performance of the subcomponents of PS in FEP patients, parents, siblings, and controls.
METHODS: Results from tests, including Trail Making Test Part A and Part B, Digit Symbol Coding Test, Grooved Pegboard Test, and Stroop Word and Stroop Color subtests, were obtained from 133 FEP patients, 146 parents, and 202 controls. Exploratory Factor Analysis (EFA) was employed in controls to establish the structure, followed by Confirmatory Factor Analysis (CFA) to verify if the other groups share this structure.
RESULTS: EFA revealed a two-factor model: Factor 1 for the motor subcomponent and Factor 2 for the cognitive subcomponent. Subsequently, CFA indicated a good fit for the remaining groups with differences in the relationship between the factors.
CONCLUSIONS: Differences in the relationships of factors within a common structure suggest the involvement of different compensatory strategies among groups, providing insights into the underlying mechanisms of PS deficits in patients and relatives.
METHODS: Results from tests, including Trail Making Test Part A and Part B, Digit Symbol Coding Test, Grooved Pegboard Test, and Stroop Word and Stroop Color subtests, were obtained from 133 FEP patients, 146 parents, and 202 controls. Exploratory Factor Analysis (EFA) was employed in controls to establish the structure, followed by Confirmatory Factor Analysis (CFA) to verify if the other groups share this structure.
RESULTS: EFA revealed a two-factor model: Factor 1 for the motor subcomponent and Factor 2 for the cognitive subcomponent. Subsequently, CFA indicated a good fit for the remaining groups with differences in the relationship between the factors.
CONCLUSIONS: Differences in the relationships of factors within a common structure suggest the involvement of different compensatory strategies among groups, providing insights into the underlying mechanisms of PS deficits in patients and relatives.
摘要：
背景：处理速度（PS）缺陷是认知障碍的一个基本方面，不仅在精神分裂症中，而且在经历第一次精神病发作（FEP）的个体及其未受影响的一级亲属中也很明显。评估PS的测试中的异质性反映了运动和认知子组件在不同程度上的参与。我们的目的是探讨FEP患者PS亚组分的表现差异，父母,兄弟姐妹,和控制。
方法：测试结果，包括跟踪测试A部分和B部分，数字符号编码测试,槽板测试,和StroopWord和StroopColor子测试，来自133名FEP患者，146父母202个控件。在对照中采用探索性因子分析(EFA)来建立结构，然后进行验证性因素分析(CFA)，以验证其他群体是否共享此结构。
结果：EFA揭示了一个双因素模型：运动子组件的因素1和认知子组件的因素2。随后，CFA表明与其余组的拟合良好，因素之间的关系存在差异。
结论：共同结构中各因素关系的差异表明，不同的补偿策略涉及群体之间，提供对患者和亲属PS缺陷的潜在机制的见解。
方法：测试结果，包括跟踪测试A部分和B部分，数字符号编码测试,槽板测试,和StroopWord和StroopColor子测试，来自133名FEP患者，146父母202个控件。在对照中采用探索性因子分析(EFA)来建立结构，然后进行验证性因素分析(CFA)，以验证其他群体是否共享此结构。
结果：EFA揭示了一个双因素模型：运动子组件的因素1和认知子组件的因素2。随后，CFA表明与其余组的拟合良好，因素之间的关系存在差异。
结论：共同结构中各因素关系的差异表明，不同的补偿策略涉及群体之间，提供对患者和亲属PS缺陷的潜在机制的见解。
