%0 Journal Article
%T Breaking Down Processing Speed: Motor and Cognitive Insights in First-Episode Psychosis and Unaffected First-Degree Relatives.
%A Yorca-Ruiz Á
%A Magdaleno Herrero R
%A de la Foz VOG
%A Murillo-García N
%A Ayesa-Arriola R
%J Span J Psychiatry Ment Health
%V 0
%N 0
%D 2024 Jun 20
%M 38908403
暂无%R 10.1016/j.sjpmh.2024.06.002
%X <B>BACKGROUND: </B>Processing Speed (PS) deficits represent a fundamental aspect of cognitive impairment, evident not only in schizophrenia but also in individuals undergoing their first episode of psychosis (FEP) and their unaffected first-degree relatives. Heterogeneity in tests assessing PS reflects the participation of motor and cognitive subcomponents to varying degrees. We aim to explore differences in performance of the subcomponents of PS in FEP patients, parents, siblings, and controls.<BR><B>METHODS: </B>Results from tests, including Trail Making Test Part A and Part B, Digit Symbol Coding Test, Grooved Pegboard Test, and Stroop Word and Stroop Color subtests, were obtained from 133 FEP patients, 146 parents, and 202 controls. Exploratory Factor Analysis (EFA) was employed in controls to establish the structure, followed by Confirmatory Factor Analysis (CFA) to verify if the other groups share this structure.<BR><B>RESULTS: </B>EFA revealed a two-factor model: Factor 1 for the motor subcomponent and Factor 2 for the cognitive subcomponent. Subsequently, CFA indicated a good fit for the remaining groups with differences in the relationship between the factors.<BR><B>CONCLUSIONS: </B>Differences in the relationships of factors within a common structure suggest the involvement of different compensatory strategies among groups, providing insights into the underlying mechanisms of PS deficits in patients and relatives.