PDF(Pubmed)
Abstract：
BACKGROUND: Polycystic ovarian syndrome (PCOS) is a widely seen reproductive and endocrinological disorder. PCOS can exert substantial effects on many aspects of an individual\'s life, including reproductive health and psychological well-being. The objective of this study was to assess the nutritional status, premenstrual syndrome, and mental health of women affected by PCOS in comparison to women without PCOS.
METHODS: A case-control observational study in Palestine included 100 PCOS patients and 200 healthy women. The collected data included socio-demographic information, medical history, premenstrual syndrome, mental health, nutritional status, and lifestyle. Anthropometric measurement and the Mediterranean Diet Adherence Screener (MEDAS) were used to evaluate the nutritional status. The General Health Questionnaire (12-GHQ) was used to evaluate the state of mental health. Premenstrual syndrome (PMS) severity was evaluated using a validated Arabic premenstrual syndrome questionnaire.
RESULTS: The study\'s findings indicated that there was a statistically significant increase in the three dimensions of PMS among participants with PCOS, p < 0.05. Similarly, PCOS patients demonstrated elevated ratings across all aspects of mental health, p < 0.05. In terms of the other variables, it has been observed that PCOS patients have a notably greater prevalence of perceived sleep disturbances and decreased adherence to the Mediterranean diet. Regression analysis revealed that PCOS is associated with mental health problems indicated by a higher GHQ score (OR: 1.09; 95% CI: 1.03; 1.16, p < 0.05), lower adherence to the MD diet (OR: 0.86; 95% CI: 0.76; 0.98, p < 0.05), and pre-menstrual syndrome, especially the physical symptoms (OR: 1.06; 95% CI: 1.003; 1.12, p < 0.05) after adjusting for age, smoking, waist-hip ratio, and body mass index (BMI).
CONCLUSIONS: The study has linked polycystic ovary syndrome to negative mental health outcomes and an increased severity of premenstrual syndrome (PMS). Additional investigation is required in order to establish a causal association between polycystic ovary syndrome (PCOS) and lifestyle behaviors within the Palestinian population. Intervention and instructional studies are necessary to investigate the efficacy of management strategies in alleviating the effects of polycystic ovary syndrome (PCOS) on both physical and mental well-being.
METHODS: A case-control observational study in Palestine included 100 PCOS patients and 200 healthy women. The collected data included socio-demographic information, medical history, premenstrual syndrome, mental health, nutritional status, and lifestyle. Anthropometric measurement and the Mediterranean Diet Adherence Screener (MEDAS) were used to evaluate the nutritional status. The General Health Questionnaire (12-GHQ) was used to evaluate the state of mental health. Premenstrual syndrome (PMS) severity was evaluated using a validated Arabic premenstrual syndrome questionnaire.
RESULTS: The study\'s findings indicated that there was a statistically significant increase in the three dimensions of PMS among participants with PCOS, p < 0.05. Similarly, PCOS patients demonstrated elevated ratings across all aspects of mental health, p < 0.05. In terms of the other variables, it has been observed that PCOS patients have a notably greater prevalence of perceived sleep disturbances and decreased adherence to the Mediterranean diet. Regression analysis revealed that PCOS is associated with mental health problems indicated by a higher GHQ score (OR: 1.09; 95% CI: 1.03; 1.16, p < 0.05), lower adherence to the MD diet (OR: 0.86; 95% CI: 0.76; 0.98, p < 0.05), and pre-menstrual syndrome, especially the physical symptoms (OR: 1.06; 95% CI: 1.003; 1.12, p < 0.05) after adjusting for age, smoking, waist-hip ratio, and body mass index (BMI).
CONCLUSIONS: The study has linked polycystic ovary syndrome to negative mental health outcomes and an increased severity of premenstrual syndrome (PMS). Additional investigation is required in order to establish a causal association between polycystic ovary syndrome (PCOS) and lifestyle behaviors within the Palestinian population. Intervention and instructional studies are necessary to investigate the efficacy of management strategies in alleviating the effects of polycystic ovary syndrome (PCOS) on both physical and mental well-being.
摘要：
背景：多囊卵巢综合征（PCOS）是一种常见的生殖和内分泌疾病。PCOS可以对个体生活的许多方面产生重大影响，包括生殖健康和心理健康。这项研究的目的是评估营养状况，经前综合症,与没有PCOS的女性相比，受PCOS影响的女性的心理健康。
方法：巴勒斯坦的病例对照观察研究包括100名PCOS患者和200名健康女性。收集的数据包括社会人口统计信息，病史,经前综合症,心理健康,营养状况,和生活方式。人体测量和地中海饮食依从性筛选器（MEDAS）用于评估营养状况。一般健康问卷（12-GHQ）用于评估心理健康状况。使用经过验证的阿拉伯经前综合征问卷评估经前综合征（PMS）的严重程度。
结果：研究结果表明，在PCOS患者中，PMS的三个维度有统计学上的显著增加，p<0.05。同样，PCOS患者在心理健康的各个方面都表现出了较高的评分，p<0.05。就其他变量而言，据观察,PCOS患者的睡眠障碍发生率明显更高,地中海饮食依从性下降.回归分析显示，PCOS与GHQ评分较高的心理健康问题相关(OR:1.09;95%CI:1.03;1.16,p<0.05)。对MD饮食的依从性较低（OR：0.86;95％CI：0.76;0.98，p<0.05），和月经前综合症，特别是调整年龄后的身体症状（OR：1.06;95％CI：1.003;1.12，p<0.05），吸烟,腰臀比,体重指数（BMI）。
结论：该研究将多囊卵巢综合征与负面的心理健康结果和经前期综合征（PMS）的严重程度增加联系起来。为了建立巴勒斯坦人口中多囊卵巢综合征（PCOS）与生活方式之间的因果关系，需要进行额外的调查。干预和指导研究对于研究管理策略在减轻多囊卵巢综合征（PCOS）对身心健康的影响方面的功效是必要的。
方法：巴勒斯坦的病例对照观察研究包括100名PCOS患者和200名健康女性。收集的数据包括社会人口统计信息，病史,经前综合症,心理健康,营养状况,和生活方式。人体测量和地中海饮食依从性筛选器（MEDAS）用于评估营养状况。一般健康问卷（12-GHQ）用于评估心理健康状况。使用经过验证的阿拉伯经前综合征问卷评估经前综合征（PMS）的严重程度。
结果：研究结果表明，在PCOS患者中，PMS的三个维度有统计学上的显著增加，p<0.05。同样，PCOS患者在心理健康的各个方面都表现出了较高的评分，p<0.05。就其他变量而言，据观察,PCOS患者的睡眠障碍发生率明显更高,地中海饮食依从性下降.回归分析显示，PCOS与GHQ评分较高的心理健康问题相关(OR:1.09;95%CI:1.03;1.16,p<0.05)。对MD饮食的依从性较低（OR：0.86;95％CI：0.76;0.98，p<0.05），和月经前综合症，特别是调整年龄后的身体症状（OR：1.06;95％CI：1.003;1.12，p<0.05），吸烟,腰臀比,体重指数（BMI）。
结论：该研究将多囊卵巢综合征与负面的心理健康结果和经前期综合征（PMS）的严重程度增加联系起来。为了建立巴勒斯坦人口中多囊卵巢综合征（PCOS）与生活方式之间的因果关系，需要进行额外的调查。干预和指导研究对于研究管理策略在减轻多囊卵巢综合征（PCOS）对身心健康的影响方面的功效是必要的。
