免疫检查点抑制剂生物标志物的研究进展与展望.
关键词: DNA damage repair defects PD-L1 antigen presentation biomarkers co-inhibitory receptors deficient mismatch repair glycosylation immune checkpoint inhibitors immunohistochemical staining microbiome microsatellite instability high plasma biomarkers tumor gene mutation burden tumor-infiltrated or peripheral T cells
Mesh : Humans Immune Checkpoint Inhibitors / therapeutic use pharmacology Neoplasms / drug therapy immunology genetics Biomarkers, Tumor / genetics metabolism Microsatellite Instability B7-H1 Antigen / metabolism antagonists & inhibitors genetics Animals Gastrointestinal Microbiome / drug effects
来 源:
DOI:10.1016/j.xcrm.2024.101621
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