关键词: Adolescent CGRP CGRP inhibitors Calcitonin gene-related peptide Calcitonin gene-related peptide inhibitors Headache Migraine Pediatric

Mesh : Humans Migraine Disorders / drug therapy Adolescent Calcitonin Gene-Related Peptide / antagonists & inhibitors Child Calcitonin Gene-Related Peptide Receptor Antagonists / pharmacology administration & dosage

来  源:   DOI:10.1016/j.pediatrneurol.2024.05.013

Abstract:
There are limited well-studied treatments for migraine in the pediatric population. Calcitonin gene-related peptide (CGRP) inhibitors are an established safe and effective treatment in adults, and use may be appropriate for pediatric patients in certain clinical situations. We describe migraine pathophysiology as it relates to CGRP, provide an overview of available medications, and discuss clinical usage in this population.
摘要:
在儿科人群中,对偏头痛的研究有限。降钙素基因相关肽(CGRP)抑制剂是成人公认的安全有效的治疗方法,在某些临床情况下,可能适用于儿科患者。我们描述了偏头痛的病理生理学,因为它与CGRP有关,提供可用药物的概述,并讨论该人群的临床使用情况。
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