雄激素剥夺治疗通过增加的脑免疫细胞浸润加剧了阿尔茨海默相关的认知衰退。
Mesh : Animals Alzheimer Disease / drug therapy pathology metabolism Male Cognitive Dysfunction / drug therapy chemically induced pathology etiology Mice Brain / drug effects pathology metabolism Humans Blood-Brain Barrier / drug effects metabolism Disease Models, Animal Androgen Antagonists / adverse effects pharmacology Prostatic Neoplasms / drug therapy pathology Natalizumab / adverse effects pharmacology therapeutic use Plaque, Amyloid / pathology drug therapy
来 源:
DOI:10.1126/sciadv.adn8709
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