Abstract：
Dendroochreatene (1), a new phenanthrene derivative with a spirolactone ring, was isolated from the whole Dendrobium ochreatum plant together with 11 known compounds (2-12). The structure of the new compound was elucidated spectroscopically and phenolic compounds were firstly reported from D. ochreatum. Moscatilin (4), major compound isolated from D. ochreatum, was found to be cytotoxic toward H460 lung-cancer cells, with an IC50 value of 147.3 ± 0.9 µM, while loddigesiinol C (7), C-α-methoxy derivative was inactive.
摘要：
石竹烯(1),一种新的带有螺内酯环的菲衍生物，与11种已知化合物（2-12）一起从整个石斛植物中分离得到。新化合物的结构已通过光谱阐明，并首次报道了D.ochreatum的酚类化合物。莫斯卡蒂林（4），从D.ochreatum中分离出的主要化合物，被发现对H460肺癌细胞有细胞毒性，IC50值为147.3±0.9µM，而洛迪希诺C(7)，C-α-甲氧基衍生物无活性。
