%0 Journal Article
%T A new phenanthrene with a spirolactone ring from Dendrobium ochreatum.
%A Khunsantiphong N
%A Thant MT
%A Pengdee C
%A Salahong T
%A Khine HEE
%A Chanvorachote P
%A Chaotham C
%A Sritularak B
%J J Asian Nat Prod Res
%V 0
%N 0
%D 2024 Jun 21
%M 38904480
%F 1.61
%R 10.1080/10286020.2024.2368831
%X Dendroochreatene (1), a new phenanthrene derivative with a spirolactone ring, was isolated from the whole Dendrobium ochreatum plant together with 11 known compounds (2-12). The structure of the new compound was elucidated spectroscopically and phenolic compounds were firstly reported from D. ochreatum. Moscatilin (4), major compound isolated from D. ochreatum, was found to be cytotoxic toward H460 lung-cancer cells, with an IC50 value of 147.3 ± 0.9 µM, while loddigesiinol C (7), C-α-methoxy derivative was inactive.