PDF(Pubmed)
Abstract：
BACKGROUND: The rise of antimicrobial resistance represents a critical threat to global health, exacerbated by the excessive and inappropriate dispensing and use of antimicrobial drugs, notably antibiotics, which specifically target bacterial infections. The surge in antibiotic consumption globally is particularly concerning in low-income and middle-income countries (LMICs), where informal healthcare providers (IPs) play a vital role in the healthcare landscape. Often the initial point of contact for healthcare-seeking individuals, IPs play a crucial role in delivering primary care services in these regions. Despite the prevalent dispensing of antibiotics by IPs in many LMICs, as highlighted by existing research, there remains a gap in the comprehensive synthesis of antibiotic dispensing practices and the influencing factors among IPs. Hence, this scoping review seeks to map and consolidate the literature regarding antibiotic dispensing and its drivers among IPs in LMICs.
METHODS: This review will follow the Joanna Briggs Institute guideline for scoping review. A comprehensive search across nine electronic databases (MEDLINE, EMBASE, SCOPUS, Global Health, CINAHL, Web of Science, LILACS, AJOL and IMSEAR) will be performed, supplemented by manual searches of reference lists of eligible publications. The search strategy will impose no constraints on study design, methodology, publication date or language. The study selection process will be reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews. The findings on antibiotic dispensing and its patterns will be synthesised and reported descriptively using tables, visuals and a narrative summary. Additionally, factors influencing antibiotic dispensing will be elucidated through both inductive and deductive content analysis methods.
BACKGROUND: Ethical approval is not required for scoping reviews. The findings will be disseminated through peer-reviewed publications and presentations at relevant conferences.
METHODS: This review will follow the Joanna Briggs Institute guideline for scoping review. A comprehensive search across nine electronic databases (MEDLINE, EMBASE, SCOPUS, Global Health, CINAHL, Web of Science, LILACS, AJOL and IMSEAR) will be performed, supplemented by manual searches of reference lists of eligible publications. The search strategy will impose no constraints on study design, methodology, publication date or language. The study selection process will be reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews. The findings on antibiotic dispensing and its patterns will be synthesised and reported descriptively using tables, visuals and a narrative summary. Additionally, factors influencing antibiotic dispensing will be elucidated through both inductive and deductive content analysis methods.
BACKGROUND: Ethical approval is not required for scoping reviews. The findings will be disseminated through peer-reviewed publications and presentations at relevant conferences.
摘要：
背景：抗菌素耐药性的上升对全球健康构成了严重威胁，由于抗菌药物的过度和不当分配和使用而加剧，尤其是抗生素，专门针对细菌感染。全球抗生素消费量的激增在低收入和中等收入国家(LMICs)尤其令人担忧。非正式医疗保健提供者(IPs)在医疗保健领域发挥着至关重要的作用。通常是寻求医疗保健的个人的最初联系点，综合方案在这些地区提供初级保健服务方面发挥着至关重要的作用。尽管在许多LMIC中，IPs普遍分配抗生素，正如现有研究所强调的那样，在抗生素配药实践和影响因素的综合综合方面仍存在差距。因此，本范围审查旨在绘制和整合有关LMICIPs中抗生素配药及其驱动因素的文献.
方法：本综述将遵循JoannaBriggsInstitute关于范围审查的指南。对九个电子数据库的全面搜索(MEDLINE，EMBASE,Scopus,全球卫生,CINAHL,WebofScience,LILACS,AJOL和IMSEAR)将被执行，通过手动搜索合格出版物的参考列表进行补充。搜索策略不会对研究设计施加任何限制，方法论，出版日期或语言。研究选择过程将根据系统审查的首选报告项目和范围审查的荟萃分析扩展进行报告。关于抗生素配药及其模式的发现将使用表格进行综合和描述性报道，视觉效果和叙述性总结。此外,影响抗生素配药的因素将通过归纳和演绎内容分析方法阐明。
背景：范围审查不需要道德批准。调查结果将通过同行评审的出版物和相关会议的介绍传播。
方法：本综述将遵循JoannaBriggsInstitute关于范围审查的指南。对九个电子数据库的全面搜索(MEDLINE，EMBASE,Scopus,全球卫生,CINAHL,WebofScience,LILACS,AJOL和IMSEAR)将被执行，通过手动搜索合格出版物的参考列表进行补充。搜索策略不会对研究设计施加任何限制，方法论，出版日期或语言。研究选择过程将根据系统审查的首选报告项目和范围审查的荟萃分析扩展进行报告。关于抗生素配药及其模式的发现将使用表格进行综合和描述性报道，视觉效果和叙述性总结。此外,影响抗生素配药的因素将通过归纳和演绎内容分析方法阐明。
背景：范围审查不需要道德批准。调查结果将通过同行评审的出版物和相关会议的介绍传播。
