PDF(Pubmed)
Abstract：
BACKGROUND: Low mechanical properties are the main limitation of glass ionomer cements (GICs). The incorporation of elastomeric micelles is expected to enhance the strength of GICs without detrimentally affecting their physical properties and biocompatibility. This study compared the chemical and mechanical properties, as well as the cytotoxicity, of elastomeric micelles-containing glass ionomer cement (DeltaFil, DT) with commonly used materials, including EQUIA Forte Fil (EF), Fuji IX GP Extra (F9), and Ketac Molar (KT).
METHODS: Powder particles of GICs were examined with SEM-EDX. Setting kinetics were assessed using ATR-FTIR. Biaxial flexural strength/modulus and Vickers surface microhardness were measured after immersion in water for 24 h and 4 weeks. The release of F, Al, Sr, and P in water over 8 weeks was analyzed using a fluoride-specific electrode and ICP-OES. The toxicity of the material extract on mouse fibroblasts was also evaluated.
RESULTS: High fluoride levels in the powder were detected with EF and F9. DT demonstrated an initial delay followed by a faster acid reaction compared to other cements, suggesting an improved snap set. DT also exhibited superior flexural strength than other materials at both 24 h and 4 weeks but lower surface microhardness (p < 0.05). EF and F9 showed higher release of F, Al, and P than DT and KT. There was no statistically significant difference in fibroblast viability among the tested materials (p > 0.05).
CONCLUSIONS: Elastomeric micelles-containing glass ionomer cement (DT) exhibited satisfactory mechanical properties and cytocompatibility compared with other materials. DT could, therefore, potentially be considered an alternative high-strength GIC for load-bearing restorations.
METHODS: Powder particles of GICs were examined with SEM-EDX. Setting kinetics were assessed using ATR-FTIR. Biaxial flexural strength/modulus and Vickers surface microhardness were measured after immersion in water for 24 h and 4 weeks. The release of F, Al, Sr, and P in water over 8 weeks was analyzed using a fluoride-specific electrode and ICP-OES. The toxicity of the material extract on mouse fibroblasts was also evaluated.
RESULTS: High fluoride levels in the powder were detected with EF and F9. DT demonstrated an initial delay followed by a faster acid reaction compared to other cements, suggesting an improved snap set. DT also exhibited superior flexural strength than other materials at both 24 h and 4 weeks but lower surface microhardness (p < 0.05). EF and F9 showed higher release of F, Al, and P than DT and KT. There was no statistically significant difference in fibroblast viability among the tested materials (p > 0.05).
CONCLUSIONS: Elastomeric micelles-containing glass ionomer cement (DT) exhibited satisfactory mechanical properties and cytocompatibility compared with other materials. DT could, therefore, potentially be considered an alternative high-strength GIC for load-bearing restorations.
摘要：
背景：低机械性能是玻璃离聚物水泥（GIC）的主要限制。预期弹性体胶束的掺入增强GIC的强度,而不会不利地影响它们的物理性质和生物相容性。这项研究比较了化学和机械性能，以及细胞毒性，含弹性体胶束的玻璃离聚物水泥(DeltaFil，DT)与常用材料，包括EQUIAForteFil(EF)，富士IXGPExtra（F9），和KetacMolar（KT）。
方法:用SEM-EDX检查GIC的粉末颗粒。使用ATR-FTIR评估凝固动力学。在水中浸泡24小时和4周后，测量双轴弯曲强度/模量和维氏表面显微硬度。F的释放,Al,Sr,使用氟化物特异性电极和ICP-OES分析8周内水中的P。还评估了材料提取物对小鼠成纤维细胞的毒性。
结果：用EF和F9检测到粉末中的高氟化物含量。与其他水泥相比，DT表现出最初的延迟，然后是更快的酸反应，建议改进的快照集。在24小时和4周时，DT也表现出比其他材料更好的弯曲强度，但表面显微硬度较低（p<0.05）。EF和F9显示出更高的F释放，Al,和P比DT和KT。在测试材料中,成纤维细胞活力没有统计学上的显著差异(p>0.05)。
结论：与其他材料相比，含弹性胶束的玻璃离聚物水泥（DT）表现出令人满意的机械性能和细胞相容性。DT可以，因此,可能被认为是承重修复的替代高强度GIC。
方法:用SEM-EDX检查GIC的粉末颗粒。使用ATR-FTIR评估凝固动力学。在水中浸泡24小时和4周后，测量双轴弯曲强度/模量和维氏表面显微硬度。F的释放,Al,Sr,使用氟化物特异性电极和ICP-OES分析8周内水中的P。还评估了材料提取物对小鼠成纤维细胞的毒性。
结果：用EF和F9检测到粉末中的高氟化物含量。与其他水泥相比，DT表现出最初的延迟，然后是更快的酸反应，建议改进的快照集。在24小时和4周时，DT也表现出比其他材料更好的弯曲强度，但表面显微硬度较低（p<0.05）。EF和F9显示出更高的F释放，Al,和P比DT和KT。在测试材料中,成纤维细胞活力没有统计学上的显著差异(p>0.05)。
结论：与其他材料相比，含弹性胶束的玻璃离聚物水泥（DT）表现出令人满意的机械性能和细胞相容性。DT可以，因此,可能被认为是承重修复的替代高强度GIC。
