PDF(Pubmed)
Abstract：
Over the years, obesity has become more commonplace and has had a substantial impact on several medical specialties, including reproductive medicine. The potential correlation between the visceral adiposity index (VAI) and infertility has yet to be determined. Women between the ages of 18 and 45 were included in this cross-sectional study, which was conducted as part of the National Health and Nutrition Examination Survey (NHANES) between 2015 and 2020. Three tertiles were used to group VAI levels. Subgroup analysis and weighted binary logistic regression were employed to investigate the independent relationship between VAI and infertility. Smooth curve fitting was used to explore nonlinear relationships. This cross-sectional study followed the criteria of the STROBE guidelines. Of the 1231 participants, 127 were infertile women aged 18-45 years. A higher VAI was associated with a higher prevalence of infertility (OR = 1.22, 95% CI:1.03-1.45), which remained consistent across all subgroups (p > 0.05 for all interactions). We demonstrated a positive nonlinear association between VAI and infertility using a smooth curve fit. A higher visceral adiposity index level is positively correlated with a higher incidence of infertility among women in the United States. Women who are infertile can be identified using the visceral obesity index, and controlling visceral obesity may help lower the chances of becoming infertile.
摘要：
多年来,肥胖变得越来越普遍，并对几个医学专业产生了重大影响，包括生殖医学。内脏肥胖指数（VAI）与不孕症之间的潜在相关性尚未确定。这项横断面研究包括18至45岁的女性，这是2015年至2020年国家健康和营养检查调查（NHANES）的一部分。使用三个三分位数对VAI水平进行分组。采用亚组分析和加权二元logistic回归分析VAI与不孕症的独立关系。平滑曲线拟合用于探索非线性关系。这项横断面研究遵循了STROBE指南的标准。在1231名参与者中，127名年龄在18-45岁之间的不孕妇女。较高的VAI与较高的不孕症患病率相关(OR=1.22,95%CI:1.03-1.45),在所有亚组中保持一致（所有相互作用的p>0.05）。我们使用平滑曲线拟合证明了VAI和不孕症之间的正非线性关联。在美国，较高的内脏肥胖指数水平与较高的不孕症发病率呈正相关。使用内脏肥胖指数可以识别不育的女性，控制内脏肥胖可能有助于降低不育的几率。
