Abstract：
We report a case of a large vestibular schwannoma in an 80-year-old female patient that shrank after palliative Gamma Knife radiosurgery (GKS). Neurological symptoms included hearing deterioration and facial palsy. The tumor volume was 21.9 mL. Craniotomy was considered high-risk, and conventional GKS was risky, owing to the risk of transient enlargement. Therefore, GKS was performed on only a portion of the tumor. The marginal dose (12 Gy) volume was 3.8 mL (17.4%). The tumor began to shrink after transient enlargement. Sixty months later, the tumor volume was only 3.1 mL, and the patient was able to maintain independent activities of daily living without salvage treatment.
摘要：
我们报告了一例80岁女性患者的大型前庭神经鞘瘤，该患者在姑息性伽玛刀放射外科（GKS）后缩小。神经系统症状包括听力恶化和面神经麻痹。肿瘤体积为21.9mL。开颅手术被认为是高风险的,传统的GKS是有风险的，由于存在短暂扩大的风险。因此,GKS仅在肿瘤的一部分上进行。边缘剂量(12Gy)体积为3.8mL(17.4%)。短暂增大后肿瘤开始缩小。60个月后,肿瘤体积只有3.1毫升,患者能够维持独立的日常生活活动而无需抢救治疗。
