Abstract：
Urinary tract infections caused by Aerococcus urinae have rarely been reported in children, and the clinical characteristics remain unclear. We reviewed medical records of children whose urine cultures grew A. urinae (≥104 CFU/mL) at a tertiary children\'s hospital in Tokyo, Japan. We found 17 pediatric patients in a review of 22,769 urine cultures between June 2006 and May 2022. The median age of 17 patients was 10.7 years (IQR 8-13 years), and males represented 76.5 % of the patients. Sixteen patients (94.1 %) had underlying urological conditions (neurogenic bladder, vesicoureteral reflux, urethral stenosis, bladder exstrophy, or urinary catheterization). The chief symptoms were fever (35.3 %), malodorous urine (23.5 %), nausea (11.8 %), and back pain (5.9 %). Ten patients were asymptomatic. Pyelonephritis was diagnosed in five male patients. All of them had underlying abnormal conditions of the bladder, and two had malodorous urine. All patients had favorable outcomes after 10-14 days of ampicillin/amoxicillin-based antimicrobial therapy.
摘要：
由尿球菌引起的尿路感染在儿童中很少报道，临床特征仍不清楚。我们回顾了在东京一家三级儿童医院的尿液培养中增加尿样（≥104CFU/mL）的儿童的医疗记录，日本。在2006年6月至2022年5月期间，我们对22,769例尿液培养进行了回顾，发现17例儿科患者。17例患者的中位年龄为10.7岁（IQR8-13岁），男性占76.5%。16例患者（94.1%）有潜在的泌尿系统疾病（神经源性膀胱，膀胱输尿管反流,尿道狭窄,膀胱外翻,或导尿）。主要症状为发热(35.3%),恶臭尿液（23.5%），恶心（11.8%），和背痛（5.9%）。10例患者无症状。在五名男性患者中诊断出肾盂肾炎。他们都有潜在的膀胱异常情况，和两个有恶臭的尿液。所有患者在氨苄西林/阿莫西林为基础的抗菌治疗10-14天后均有良好的预后。
