{Reference Type}: Journal Article
{Title}: Characteristics of urinary tract infections in children with positive urine culture for Aerococcusurinae.
{Author}: Sato E;Iijima H;Shoji K;Ishiguro A;Ogimi C;
{Journal}: J Infect Chemother
{Volume}: 0
{Issue}: 0
{Year}: 2024 Jun 18
{Factor}: 2.065
{DOI}: 10.1016/j.jiac.2024.06.010
{Abstract}: Urinary tract infections caused by Aerococcus urinae have rarely been reported in children, and the clinical characteristics remain unclear. We reviewed medical records of children whose urine cultures grew A. urinae (≥104 CFU/mL) at a tertiary children's hospital in Tokyo, Japan. We found 17 pediatric patients in a review of 22,769 urine cultures between June 2006 and May 2022. The median age of 17 patients was 10.7 years (IQR 8-13 years), and males represented 76.5 % of the patients. Sixteen patients (94.1 %) had underlying urological conditions (neurogenic bladder, vesicoureteral reflux, urethral stenosis, bladder exstrophy, or urinary catheterization). The chief symptoms were fever (35.3 %), malodorous urine (23.5 %), nausea (11.8 %), and back pain (5.9 %). Ten patients were asymptomatic. Pyelonephritis was diagnosed in five male patients. All of them had underlying abnormal conditions of the bladder, and two had malodorous urine. All patients had favorable outcomes after 10-14 days of ampicillin/amoxicillin-based antimicrobial therapy.