PDF(Pubmed)
Abstract：
This study investigates disparities in chemotherapy treatment for unresectable non-small cell lung cancer (NSCLC) between urban and rural populations. Despite advancements in NSCLC treatments enhancing survival, significant inequities persist, notably in rural areas where access to care is often limited, resulting in poorer outcomes. Through a systematic review and meta-analysis, we analyzed data from selected studies that compare chemotherapy access and usage between these populations from 2010 to 2024. Our findings indicate that rural patients are consistently less likely to receive advanced chemotherapy treatments than urban counterparts, with a pooled odds ratio of 0.91 (95% confidence interval (CI): 0.83-1.00), suggesting a marginal but noticeable disparity. This highlights a crucial gap in healthcare provision, underscoring the need for policy interventions and improved healthcare practices to ensure equitable treatment access. This research calls for further investigation into socioeconomic and cultural factors contributing to these disparities to inform targeted improvement strategies.
摘要：
这项研究调查了城乡人群中不可切除的非小细胞肺癌（NSCLC）的化疗治疗差异。尽管在NSCLC治疗方面取得了进步，提高了生存率，严重的不平等仍然存在，特别是在农村地区，获得护理的机会往往有限，导致较差的结果。通过系统回顾和荟萃分析，我们分析了部分研究的数据,这些研究比较了2010年至2024年间这些人群的化疗机会和使用情况.我们的研究结果表明，与城市患者相比，农村患者接受高级化疗的可能性一直较小。合并比值比为0.91(95%置信区间(CI)：0.83-1.00)，暗示了一个边缘但明显的差距。这凸显了医疗保健供应方面的关键差距，强调需要采取政策干预措施和改进医疗保健做法，以确保公平获得治疗。这项研究要求进一步调查导致这些差异的社会经济和文化因素，以提供有针对性的改进策略。
