PDF(Pubmed)
Abstract：
The pathophysiology of Adolescent Idiopathic Scoliosis (AIS) is not yet fully understood, but multifactorial hypotheses have been proposed that include defective central nervous system (CNS) control of posture, biomechanics, and body schema alterations. To deepen CNS control of posture in AIS, electroencephalographic (EEG) activity during a simple balance task in adolescents with and without AIS was parsed into EEG microstates. Microstates are quasi-stable spatial distributions of the electric potential of the brain that last tens of milliseconds. The spatial distribution of the EEG characterised by the orientation from left-frontal to right-posterior remains stable for a greater amount of time in AIS compared to controls. This spatial distribution of EEG, commonly named in the literature as class B, has been found to be correlated with the visual resting state network. Both vision and proprioception networks provide critical information in mapping the extrapersonal environment. This neurophysiological marker probably unveils an alteration in the postural control mechanism in AIS, suggesting a higher information processing load due to the increased postural demands caused by scoliosis.
摘要：
青少年特发性脊柱侧凸（AIS）的病理生理学尚未完全了解，但是已经提出了多因素假设，包括有缺陷的中枢神经系统（CNS）姿势控制，生物力学,和身体模式改变。为了加深中枢神经系统对AIS姿势的控制，在有和没有AIS的青少年中进行简单平衡任务时的脑电图（EEG）活动被解析为EEG微状态。微状态是持续几十毫秒的大脑电势的准稳定空间分布。与对照相比，以从左额叶到右后部的方向为特征的EEG的空间分布在AIS中保持稳定更长时间。脑电图的这种空间分布，在文献中通常被称为B类，已经发现与视觉静息状态网络相关。视觉和本体感觉网络在绘制外部环境时都提供了关键信息。这种神经生理学标记可能揭示了AIS中姿势控制机制的改变，提示由于脊柱侧弯引起的姿势需求增加，信息处理负荷更高。
