Abstract：
UNASSIGNED: To evaluate the efficacy of Mohs micrographic surgery (MMS) combined with photodynamic therapy (PDT) in treating non-invasive extramammary Paget\'s disease (EMPD).
UNASSIGNED: A 77-year-old male patient with non-invasive EMPD was treated with MMS followed by PDT. Preoperative fluorescence localization using 5-aminolevulinic acid (ALA) was performed to determine the surgical scope. MMS was conducted under lumbar anesthesia with intraoperative frozen-section pathology. Postoperative PDT was administered weekly for three sessions.
UNASSIGNED: The patient achieved negative surgical margins after two rounds of intraoperative pathology. Postoperative follow-up over two years showed no recurrence, and the patient did not experience significant adverse reactions.
UNASSIGNED: The combination of MMS and PDT was effective in treating non-invasive EMPD, demonstrating favorable clinical outcomes and no recurrence over the two-year follow-up period.
UNASSIGNED: A 77-year-old male patient with non-invasive EMPD was treated with MMS followed by PDT. Preoperative fluorescence localization using 5-aminolevulinic acid (ALA) was performed to determine the surgical scope. MMS was conducted under lumbar anesthesia with intraoperative frozen-section pathology. Postoperative PDT was administered weekly for three sessions.
UNASSIGNED: The patient achieved negative surgical margins after two rounds of intraoperative pathology. Postoperative follow-up over two years showed no recurrence, and the patient did not experience significant adverse reactions.
UNASSIGNED: The combination of MMS and PDT was effective in treating non-invasive EMPD, demonstrating favorable clinical outcomes and no recurrence over the two-year follow-up period.
摘要：
■评估Mohs显微手术（MMS）联合光动力疗法（PDT）治疗非侵入性乳房外Paget病（EMPD）的疗效。
■一名77岁男性非侵入性EMPD患者接受MMS治疗，随后接受PDT治疗。使用5-氨基乙酰丙酸（ALA）进行术前荧光定位以确定手术范围。MMS在腰麻下进行，术中冰冻切片病理。术后每周进行一次PDT，共进行三次。
■经过两轮术中病理检查，患者获得阴性手术切缘。术后随访两年以上无复发,患者未出现明显不良反应。
■MMS和PDT的组合可有效治疗非侵入性EMPD，在2年的随访期内，显示良好的临床结局和无复发。
■一名77岁男性非侵入性EMPD患者接受MMS治疗，随后接受PDT治疗。使用5-氨基乙酰丙酸（ALA）进行术前荧光定位以确定手术范围。MMS在腰麻下进行，术中冰冻切片病理。术后每周进行一次PDT，共进行三次。
■经过两轮术中病理检查，患者获得阴性手术切缘。术后随访两年以上无复发,患者未出现明显不良反应。
■MMS和PDT的组合可有效治疗非侵入性EMPD，在2年的随访期内，显示良好的临床结局和无复发。
