{Reference Type}: Case Reports
{Title}: Preliminary analysis of the efficacy of Mohs micrographic surgery combined with photodynamic therapy in a case of noninvasive extramammary Paget's disease.
{Author}: Han L;Jiang Y;Wan M;
{Journal}: J Dermatolog Treat
{Volume}: 35
{Issue}: 1
{Year}: 2024 Dec
{Factor}: 3.23
{DOI}: 10.1080/09546634.2024.2368066
{Abstract}: <B>UNASSIGNED: </B>To evaluate the efficacy of Mohs micrographic surgery (MMS) combined with photodynamic therapy (PDT) in treating non-invasive extramammary Paget's disease (EMPD).<BR><B>UNASSIGNED: </B>A 77-year-old male patient with non-invasive EMPD was treated with MMS followed by PDT. Preoperative fluorescence localization using 5-aminolevulinic acid (ALA) was performed to determine the surgical scope. MMS was conducted under lumbar anesthesia with intraoperative frozen-section pathology. Postoperative PDT was administered weekly for three sessions.<BR><B>UNASSIGNED: </B>The patient achieved negative surgical margins after two rounds of intraoperative pathology. Postoperative follow-up over two years showed no recurrence, and the patient did not experience significant adverse reactions.<BR><B>UNASSIGNED: </B>The combination of MMS and PDT was effective in treating non-invasive EMPD, demonstrating favorable clinical outcomes and no recurrence over the two-year follow-up period.