PDF(Pubmed)
Abstract：
This manuscript describes the Advanced Breast Cancer (ABC) international consensus guidelines updated at the last two ABC international consensus conferences (ABC 6 in 2021, virtual, and ABC 7 in 2023, in Lisbon, Portugal), organized by the ABC Global Alliance. It provides the main recommendations on how to best manage patients with advanced breast cancer (inoperable locally advanced or metastatic), of all breast cancer subtypes, as well as palliative and supportive care. These guidelines are based on available evidence or on expert opinion when a higher level of evidence is lacking. Each guideline is accompanied by the level of evidence (LoE), grade of recommendation (GoR) and percentage of consensus reached at the consensus conferences. Updated diagnostic and treatment algorithms are also provided. The guidelines represent the best management options for patients living with ABC globally, assuming accessibility to all available therapies. Their adaptation (i.e. resource-stratified guidelines) is often needed in settings where access to care is limited.
摘要：
本手稿描述了在最近两次ABC国际共识会议上更新的晚期乳腺癌（ABC）国际共识指南（ABC6于2021年，虚拟，2023年在里斯本的ABC7，葡萄牙),由ABC全球联盟组织。它提供了关于如何最好地管理晚期乳腺癌患者（无法手术的局部晚期或转移性）的主要建议，在所有乳腺癌亚型中，以及姑息治疗和支持治疗。这些指南基于现有证据或缺乏更高水平证据时的专家意见。每个指南都附有证据水平(LoE)，推荐等级(GoR)和在共识会议上达成共识的百分比。还提供了更新的诊断和治疗算法。该指南代表了全球ABC患者的最佳管理选择，假设可以使用所有可用的治疗方法。在获得护理的机会有限的环境中，通常需要对其进行调整（即资源分层指南）。
