Abstract：
OBJECTIVE: This study aims to investigate the joint effects of cancer and sleep disorders on the health-related quality of life (HRQoL), healthcare resource utilization, and expenditures among US adults.
METHODS: Utilizing the 2018-2019 Medical Expenditure Panel Survey (MEPS) database, a sample of 25,274 participants was categorized into four groups based on cancer and sleep disorder status. HRQoL was assessed using the VR-12 questionnaire. Generalized linear model (GLM) with a log-linear regression model combined gamma distribution was applied for the analysis of healthcare expenditure data.
RESULTS: Individuals with both cancer and sleep disorders (C+/S+) exhibited notably lower physical health (PCS) and mental health (MCS) scores-1.45 and 1.87 points lower, respectively. They also showed significantly increased clinic visits (2.12 times), outpatient visits (3.59 times), emergency visits (1.69 times), and total medical expenditures (2.08 times) compared to those without cancer or sleep disorders (C-/S-). In contrast, individuals with sleep disorders alone (C-/S+) had the highest number of prescription drug usage (2.26 times) and home health care days (1.76 times) compared to the reference group (C-/S-).
CONCLUSIONS: Regardless of cancer presence, individuals with sleep disorders consistently reported compromised HRQoL. Furthermore, those with cancer and sleep disorders experienced heightened healthcare resource utilization, underscoring the considerable impact of sleep disorders on overall quality of life.
CONCLUSIONS: The findings of this study address the importance of sleep disorders among cancer patients and their potential implications for cancer care. Healthcare professionals should prioritize screening, education, and tailored interventions to support sleep health in this population.
METHODS: Utilizing the 2018-2019 Medical Expenditure Panel Survey (MEPS) database, a sample of 25,274 participants was categorized into four groups based on cancer and sleep disorder status. HRQoL was assessed using the VR-12 questionnaire. Generalized linear model (GLM) with a log-linear regression model combined gamma distribution was applied for the analysis of healthcare expenditure data.
RESULTS: Individuals with both cancer and sleep disorders (C+/S+) exhibited notably lower physical health (PCS) and mental health (MCS) scores-1.45 and 1.87 points lower, respectively. They also showed significantly increased clinic visits (2.12 times), outpatient visits (3.59 times), emergency visits (1.69 times), and total medical expenditures (2.08 times) compared to those without cancer or sleep disorders (C-/S-). In contrast, individuals with sleep disorders alone (C-/S+) had the highest number of prescription drug usage (2.26 times) and home health care days (1.76 times) compared to the reference group (C-/S-).
CONCLUSIONS: Regardless of cancer presence, individuals with sleep disorders consistently reported compromised HRQoL. Furthermore, those with cancer and sleep disorders experienced heightened healthcare resource utilization, underscoring the considerable impact of sleep disorders on overall quality of life.
CONCLUSIONS: The findings of this study address the importance of sleep disorders among cancer patients and their potential implications for cancer care. Healthcare professionals should prioritize screening, education, and tailored interventions to support sleep health in this population.
摘要：
目的：本研究旨在探讨癌症和睡眠障碍对健康相关生活质量（HRQoL）的联合影响。医疗保健资源利用，以及美国成年人的支出。
方法：利用2018-2019年医疗支出小组调查(MEPS)数据库，根据癌症和睡眠障碍状况,我们将25,274名参与者的样本分为四组.使用VR-12问卷评估HRQoL。结合伽马分布的对数线性回归模型的广义线性模型（GLM）用于医疗支出数据的分析。
结果：患有癌症和睡眠障碍（C/S）的人表现出明显较低的身体健康（PCS）和心理健康（MCS）得分-1.45分和1.87分，分别。他们还显示诊所就诊次数显着增加（2.12倍），门诊(3.59次)，紧急访问（1.69次），与没有癌症或睡眠障碍的患者（C-/S-）相比，医疗总支出（2.08倍）。相比之下,与参照组(C-/S-)相比,单独患有睡眠障碍的个体(C-/S+)的处方药使用量(2.26倍)和家庭保健天数(1.76倍)最高.
结论：无论是否存在癌症，睡眠障碍患者始终报告HRQoL受损。此外，那些患有癌症和睡眠障碍的人经历了医疗资源利用率的提高，强调睡眠障碍对整体生活质量的显著影响。
结论：本研究的结果阐述了癌症患者睡眠障碍的重要性及其对癌症治疗的潜在影响。医疗保健专业人员应该优先考虑筛查，教育,和量身定制的干预措施，以支持该人群的睡眠健康。
方法：利用2018-2019年医疗支出小组调查(MEPS)数据库，根据癌症和睡眠障碍状况,我们将25,274名参与者的样本分为四组.使用VR-12问卷评估HRQoL。结合伽马分布的对数线性回归模型的广义线性模型（GLM）用于医疗支出数据的分析。
结果：患有癌症和睡眠障碍（C/S）的人表现出明显较低的身体健康（PCS）和心理健康（MCS）得分-1.45分和1.87分，分别。他们还显示诊所就诊次数显着增加（2.12倍），门诊(3.59次)，紧急访问（1.69次），与没有癌症或睡眠障碍的患者（C-/S-）相比，医疗总支出（2.08倍）。相比之下,与参照组(C-/S-)相比,单独患有睡眠障碍的个体(C-/S+)的处方药使用量(2.26倍)和家庭保健天数(1.76倍)最高.
结论：无论是否存在癌症，睡眠障碍患者始终报告HRQoL受损。此外，那些患有癌症和睡眠障碍的人经历了医疗资源利用率的提高，强调睡眠障碍对整体生活质量的显著影响。
结论：本研究的结果阐述了癌症患者睡眠障碍的重要性及其对癌症治疗的潜在影响。医疗保健专业人员应该优先考虑筛查，教育,和量身定制的干预措施，以支持该人群的睡眠健康。
