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Abstract：
UNASSIGNED: The Hepatitis C virus (HCV) infection is strongly associated with cardiovascular disease risk factors, but the relationship with blood pressure (BP) remains unclear.
UNASSIGNED: To assess the association between HCV infection status and BP in US adults.
UNASSIGNED: Data for the study were obtained from the National Health and Nutrition Examination Survey (NHANES) between 1999 and 2012. The association of HCV infection status (including HCV infection, current HCV infection, and past HCV infection) with hypertension, systolic blood pressure (SBP), and diastolic blood pressure (DBP) were explored using logistic or linear regression analyses respectively.
UNASSIGNED: A total of 25,850 participants (age≥18 years) were enrolled in the current study, including 14,162 participants with hypertension. After adjusting for all covariates, HCV infection/current HCV infection was not associated with hypertension and SBP compared to participants with non-HCV infection (OR: 1.34,95% CI 0.96-1.87/1.31 95% CI 0.91,1.91, β: -0.92, 95% CI -2.7-0.86/-0.35 95% CI -2.51,1.81, respectively). HCV infection/current HCV infection was only associated with elevated DBP (β: 4.1,95% CI 2.57-5.63/4.24,95% CI 2.27-6.21). However, there was no correlation with past HCV infection in participants with hypertension, SBP, and DBP compared to those with non-HCV infection (OR: 1.23,95% CI 0.59-2.54; β: -3.79, 95% CI -7.67-0.08 and 2.28 95% CI -0.36-4.92, respectively).
UNASSIGNED: In a representative sample of US adults, it was found that both HCV infection and current HCV infection were independently linked to higher DBP. However, there was no association between past HCV infection and DBP.
UNASSIGNED: To assess the association between HCV infection status and BP in US adults.
UNASSIGNED: Data for the study were obtained from the National Health and Nutrition Examination Survey (NHANES) between 1999 and 2012. The association of HCV infection status (including HCV infection, current HCV infection, and past HCV infection) with hypertension, systolic blood pressure (SBP), and diastolic blood pressure (DBP) were explored using logistic or linear regression analyses respectively.
UNASSIGNED: A total of 25,850 participants (age≥18 years) were enrolled in the current study, including 14,162 participants with hypertension. After adjusting for all covariates, HCV infection/current HCV infection was not associated with hypertension and SBP compared to participants with non-HCV infection (OR: 1.34,95% CI 0.96-1.87/1.31 95% CI 0.91,1.91, β: -0.92, 95% CI -2.7-0.86/-0.35 95% CI -2.51,1.81, respectively). HCV infection/current HCV infection was only associated with elevated DBP (β: 4.1,95% CI 2.57-5.63/4.24,95% CI 2.27-6.21). However, there was no correlation with past HCV infection in participants with hypertension, SBP, and DBP compared to those with non-HCV infection (OR: 1.23,95% CI 0.59-2.54; β: -3.79, 95% CI -7.67-0.08 and 2.28 95% CI -0.36-4.92, respectively).
UNASSIGNED: In a representative sample of US adults, it was found that both HCV infection and current HCV infection were independently linked to higher DBP. However, there was no association between past HCV infection and DBP.
摘要：
■丙型肝炎病毒（HCV）感染与心血管疾病的危险因素密切相关，但与血压（BP）的关系仍不清楚。
■评估美国成年人HCV感染状态与BP之间的关联。
■该研究的数据来自1999年至2012年的国家健康和营养检查调查（NHANES）。HCV感染状态（包括HCV感染，当前HCV感染，和过去的HCV感染）伴有高血压，收缩压（SBP），和舒张压（DBP）分别使用logistic或线性回归分析。
■本研究共纳入25,850名参与者（年龄≥18岁），包括14,162名高血压患者。在调整所有协变量后，与非HCV感染的参与者相比，HCV感染/当前HCV感染与高血压和SBP无关（OR：1.34,95％CI0.96-1.87/1.3195％CI0.91,1.91，β：-0.92，95％CI-2.7-0.86/-0.3595％CI-2.51,1.81）。HCV感染/当前HCV感染仅与DBP升高相关(β:4.1,95%CI2.57-5.63/4.24,95%CI2.27-6.21)。然而,高血压患者与既往HCV感染无相关性,SBP,和DBP与非HCV感染患者相比（OR：1.23,95％CI0.59-2.54；β：-3.79，95％CI-7.67-0.08和2.2895％CI-0.36-4.92）。
■在美国成年人的代表性样本中，研究发现,HCV感染和当前HCV感染均与较高的DBP独立相关.然而,既往HCV感染与DBP无相关性.
■评估美国成年人HCV感染状态与BP之间的关联。
■该研究的数据来自1999年至2012年的国家健康和营养检查调查（NHANES）。HCV感染状态（包括HCV感染，当前HCV感染，和过去的HCV感染）伴有高血压，收缩压（SBP），和舒张压（DBP）分别使用logistic或线性回归分析。
■本研究共纳入25,850名参与者（年龄≥18岁），包括14,162名高血压患者。在调整所有协变量后，与非HCV感染的参与者相比，HCV感染/当前HCV感染与高血压和SBP无关（OR：1.34,95％CI0.96-1.87/1.3195％CI0.91,1.91，β：-0.92，95％CI-2.7-0.86/-0.3595％CI-2.51,1.81）。HCV感染/当前HCV感染仅与DBP升高相关(β:4.1,95%CI2.57-5.63/4.24,95%CI2.27-6.21)。然而,高血压患者与既往HCV感染无相关性,SBP,和DBP与非HCV感染患者相比（OR：1.23,95％CI0.59-2.54；β：-3.79，95％CI-7.67-0.08和2.2895％CI-0.36-4.92）。
■在美国成年人的代表性样本中，研究发现,HCV感染和当前HCV感染均与较高的DBP独立相关.然而,既往HCV感染与DBP无相关性.
