PDF(Pubmed)
Abstract：
The accuracy and efficacy of laser ablation procedures depend on the accurate placement of the laser applicator within the diseased tissue, monitoring the real-time temperature during the ablation procedure, and mapping the extent of the ablated region. Ultrasound (US) imaging has been widely used to guide ablation procedures. While US imaging offers significant advantages for guiding ablation procedures, its limitations include low imaging contrast, angular dependency, and limited ability to monitor the temperature. Photoacoustic (PA) imaging is a relatively new imaging modality that inherits the advantages of US imaging and offers enhanced capabilities for laser-guided ablations, such as accurate, angle-independent tracking of ablation catheters, the potential for quantitative thermometry, and monitoring thermal lesion formation. This work provides an overview of ultrasound-guided procedures and how different US-related artifacts limit their utility, followed by introducing PA as complementary to US as a solution to address the existing limitations and improve ablation outcomes. Furthermore, we highlight the integration of PA-driven features into existing US-guided laser ablation systems, along with their limitations and future outlooks. Integrated US/PA-guided laser ablation procedures can lead to safer and more precise treatment outcomes.
摘要：
激光消融程序的准确性和有效性取决于激光施加器在患病组织内的准确放置。监测消融过程中的实时温度，并绘制消融区域的范围。超声(US)成像已被广泛用于指导消融程序。尽管US成像在指导消融手术方面具有显著优势,它的局限性包括低成像对比度，角度依赖性，和有限的能力来监测温度。光声（PA）成像是一种相对较新的成像方式，继承了美国成像的优点，并为激光制导消融提供了增强的功能，如准确，独立于角度的消融导管跟踪，定量测温的潜力，并监测热损伤的形成。这项工作提供了超声引导程序的概述，以及不同的US相关伪影如何限制其效用。随后引入PA作为US的补充,作为解决现有局限性和改善消融结果的解决方案.此外，我们强调将PA驱动的功能集成到现有的美国制导激光烧蚀系统中，以及他们的局限性和未来展望。集成的US/PA引导的激光消融程序可以导致更安全和更精确的治疗结果。
