PDF(Pubmed)
Abstract：
Background: Managing vertebral metastases (VM) is still challenging in oncology, necessitating the use of effective surgical strategies to preserve patient quality of life (QoL). Traditional open posterior fusion (OPF) and percutaneous osteosynthesis (PO) are well-documented approaches, but their comparative efficacy remains debated. Methods: This retrospective study compared short-term outcomes (6-12 months) between OPF and PO in 78 cancer patients with spinal metastases. This comprehensive evaluation included functional, clinical, and radiographic parameters. Statistical analysis utilized PRISM software (version 10), with significance set at p < 0.05. Results: PO demonstrated advantages over OPF, including shorter surgical durations, reduced blood loss, and hospital stay, along with lower perioperative complication rates. Patient quality of life and functional outcomes favored PO, particularly at the 6-month mark. The mortality rates at one year were significantly lower in the PO group. Conclusions: Minimally invasive techniques offer promising benefits in VM management, optimizing patient outcomes and QoL. Despite limitations, this study advocates for the adoption of minimally invasive approaches to enhance the care of multi-metastatic patients with symptomatic VM.
摘要：
背景：治疗椎体转移瘤（VM）在肿瘤学中仍然具有挑战性，需要使用有效的手术策略来保持患者的生活质量（QoL）。传统的开放后路融合术（OPF）和经皮接骨术（PO）是有据可查的方法，但它们的相对功效仍存在争议。方法：这项回顾性研究比较了OPF和PO在78例脊柱转移癌患者中的短期结果（6-12个月）。这一综合评价包括功能，临床,和射线照相参数。使用PRISM软件（版本10）进行统计分析，显著性设置为p<0.05。结果：PO比OPF具有优势，包括较短的手术持续时间，减少失血,住院，围手术期并发症发生率较低。患者的生活质量和功能结果有利于PO，特别是在6个月的时候。PO组一年的死亡率明显较低。结论：微创技术在虚拟机管理中提供了有希望的好处，优化患者预后和QoL。尽管有局限性,本研究主张采用微创方法,以加强对有症状的VM多转移患者的护理.
