PDF(Pubmed)
Abstract：
Background: Substance use disorders present a tremendous challenge within contemporary healthcare systems. Specifically, in the domain of opioid use disorders (OUDs), several foundational elements are crucial for the efficacious management of afflicted individuals. Regrettably, the premature discontinuation of inpatient opioid withdrawal treatment is a prevalent phenomenon. This study aims to elucidate the prevalence of the premature termination of inpatient opioid withdrawal treatment among patients with comorbid ADHD. Methods: We conducted a comprehensive assessment of all participants currently undergoing inpatient opioid withdrawal treatment. Our assessment protocol included the administration of the ADHD Self-Report Scale (ADHD-SR) and the Wender Utah Rating Scale (WURS-k). Additionally, participants who met the thresholds on one or both questionnaires underwent further evaluation using the Diagnostic Interview for ADHD in Adults (DIVA-2.0). Results: The prevalence of individuals diagnosed with ADHD within the studied cohort was determined to be 29.3%. Among the subset of participants identified as ADHD-positive, a notable 54.5% prematurely ceased therapy. In contrast, among those identified as ADHD-negative, the premature discontinuation rate was substantially lower at 28.3%. Conclusions: In summary, the impact of ADHD as a comorbid condition on the efficacy of inpatient opioid withdrawal treatment has been underscored. By identifying comorbid ADHD early in the treatment process, tailored therapeutic approaches may help to maximize the effectiveness of interventions and may improve patient outcomes. This underscores the importance of proactive screening for ADHD as a psychiatric comorbidity in optimizing the management of individuals undergoing inpatient opioid withdrawal treatment.
摘要：
背景：物质使用障碍在当代医疗保健系统中提出了巨大的挑战。具体来说,在阿片类药物使用障碍（OUD）领域，几个基本要素对于有效管理患病个体至关重要。遗憾的是,过早停止住院阿片类药物戒断治疗是一种普遍现象。本研究旨在阐明共病ADHD患者中过早终止住院阿片类药物戒断治疗的患病率。方法：我们对目前正在接受住院阿片类药物戒断治疗的所有参与者进行了全面评估。我们的评估方案包括ADHD自我报告量表（ADHD-SR）和WenderUtah评定量表（WURS-k）的管理。此外,使用成人ADHD诊断性访谈(DIVA-2.0)对一项或两项问卷均达到阈值的参与者进行了进一步评估.结果：研究队列中诊断为ADHD的个体的患病率为29.3％。在被确定为ADHD阳性的参与者的子集中，值得注意的54.5%的人过早停止治疗。相比之下,在那些被确定为多动症阴性的人中，过早停药率明显低于28.3%.结论：总之，已强调ADHD作为合并症对住院阿片类药物戒断治疗疗效的影响.通过在治疗过程的早期发现合并症，量身定制的治疗方法可能有助于最大限度地提高干预措施的有效性，并可能改善患者的预后。这强调了积极筛查ADHD作为精神病合并症的重要性，以优化接受住院阿片类药物戒断治疗的个人的管理。
