PDF(Pubmed)
Abstract：
BACKGROUND: Mycoplasma pneumoniae pneumonia is a common respiratory infection among children. However, the occurrence of thromboembolism with plastic bronchitis in association with Mycoplasma pneumoniae pneumonia is extremely rare. This case series presents five cases of children with Mycoplasma pneumoniae pneumonia who developed thromboembolism and plastic bronchitis. The clinical presentation, diagnostic approach, and management strategies are discussed.
METHODS: A retrospective analysis was conducted on medical records from a pediatric hospital. Patient demographics, clinical features, laboratory findings, imaging results, treatment modalities, and outcomes were collected.
RESULTS: The patients in our case series presented with varying degrees of respiratory distress, cough, and fever. Imaging studies revealed evidence of thromboembolism based on pulmonary artery occlusion. Bronchial casts were observed by bronchoscopy. Laboratory tests demonstrated elevated D-dimer levels and fibrinogen degradation products. All patients received a combination of low molecular weight heparin anticoagulation and supportive care.
CONCLUSIONS: Thromboembolism with plastic bronchitis associated with Mycoplasma pneumoniae pneumonia is a rare but potentially serious complication in children. Prompt recognition and management are crucial for improving patient outcomes. This case series highlights the diverse clinical presentations, diagnostic challenges, and treatment strategies for this unique clinical entity. Further research is needed to better understand the pathogenesis and optimal management of this condition.
METHODS: A retrospective analysis was conducted on medical records from a pediatric hospital. Patient demographics, clinical features, laboratory findings, imaging results, treatment modalities, and outcomes were collected.
RESULTS: The patients in our case series presented with varying degrees of respiratory distress, cough, and fever. Imaging studies revealed evidence of thromboembolism based on pulmonary artery occlusion. Bronchial casts were observed by bronchoscopy. Laboratory tests demonstrated elevated D-dimer levels and fibrinogen degradation products. All patients received a combination of low molecular weight heparin anticoagulation and supportive care.
CONCLUSIONS: Thromboembolism with plastic bronchitis associated with Mycoplasma pneumoniae pneumonia is a rare but potentially serious complication in children. Prompt recognition and management are crucial for improving patient outcomes. This case series highlights the diverse clinical presentations, diagnostic challenges, and treatment strategies for this unique clinical entity. Further research is needed to better understand the pathogenesis and optimal management of this condition.
摘要：
背景：肺炎支原体肺炎是儿童常见的呼吸道感染。然而,与肺炎支原体肺炎相关的塑性支气管炎血栓栓塞的发生极为罕见.本病例系列介绍了5例肺炎支原体肺炎患儿发生血栓栓塞和塑性支气管炎。临床表现，诊断方法，并讨论了管理策略。
方法：对某儿科医院的病历进行回顾性分析。患者人口统计学，临床特征,实验室发现,成像结果,治疗方式，并收集结果。
结果：我们的病例系列中的患者出现不同程度的呼吸窘迫，咳嗽,和发烧。影像学检查显示，肺动脉闭塞有血栓栓塞的证据。通过支气管镜观察支气管管型。实验室测试表明D-二聚体水平和纤维蛋白原降解产物升高。所有患者均接受低分子肝素抗凝和支持治疗的组合。
结论：在儿童中，与肺炎支原体肺炎相关的可塑性支气管炎血栓栓塞是一种罕见但潜在的严重并发症。及时的识别和管理对于改善患者预后至关重要。这个病例系列突出了不同的临床表现，诊断挑战，以及这个独特的临床实体的治疗策略。需要进一步的研究来更好地了解这种疾病的发病机理和最佳管理。
方法：对某儿科医院的病历进行回顾性分析。患者人口统计学，临床特征,实验室发现,成像结果,治疗方式，并收集结果。
结果：我们的病例系列中的患者出现不同程度的呼吸窘迫，咳嗽,和发烧。影像学检查显示，肺动脉闭塞有血栓栓塞的证据。通过支气管镜观察支气管管型。实验室测试表明D-二聚体水平和纤维蛋白原降解产物升高。所有患者均接受低分子肝素抗凝和支持治疗的组合。
结论：在儿童中，与肺炎支原体肺炎相关的可塑性支气管炎血栓栓塞是一种罕见但潜在的严重并发症。及时的识别和管理对于改善患者预后至关重要。这个病例系列突出了不同的临床表现，诊断挑战，以及这个独特的临床实体的治疗策略。需要进一步的研究来更好地了解这种疾病的发病机理和最佳管理。
