Abstract：
OBJECTIVE: Intraocular irrigating solution is extensively applied in cataract surgery. This paper explored the difference and relationship between optical coherence tomography (OCT) and optical quality analysis system (OQAS) parameters induced by compound electrolyte intraocular irrigating solution (CEIIS) or Ringer lactate (RL) solution during uncomplicated cataract surgery.
METHODS: Totally 200 senior cataract patients were randomly divided into the CEIIS and RL groups (N = 100 patients/group). The anterior chamber was irrigated by CEIIS or RL during phacoemulsification. Patients were subdivided into diabetes mellitus (DM)+ and DM- groups. The central macular thickness (CMT), hyper reflective foci (HF), modulation transfer function cutoff frequency (MTF cutoff), Strehl ratio (SR), objective scatter index (OSI), and OQAS values (OVs) at 100%, 20%, and 9% contrast levels were measured preoperatively and 1 day and 1 week after operation using spectral-domain optical coherence tomography and OQAS II, respectively. Best-corrected visual acuity (BCVA) was assessed using the Snellen scale, followed by statistical analysis of its logarithm of the minimal angle of resolution.
RESULTS: There were no significant differences in clinical characteristics between the CEIIS and RL groups. Both groups exhibited notably increased postoperative CMT, MTF cutoff, SR, OV at 100%, 20%, and 9% contrast levels, and reduced OSI, indicating CEIIS and RL improved postoperative visual quality. CEIIS surpassed RL solution in improving postoperative visual quality, decelerating the increase of macular HF numbers and CMT in DM+ patients and postoperative BCVA. There was no difference between CEIIS and RL in long-term vision improvement.
CONCLUSIONS: CEIIS surpasses RL in postoperative visual recovery and retards increases of macular HF numbers and CMT in senior DM+ cataract patients.
METHODS: Totally 200 senior cataract patients were randomly divided into the CEIIS and RL groups (N = 100 patients/group). The anterior chamber was irrigated by CEIIS or RL during phacoemulsification. Patients were subdivided into diabetes mellitus (DM)+ and DM- groups. The central macular thickness (CMT), hyper reflective foci (HF), modulation transfer function cutoff frequency (MTF cutoff), Strehl ratio (SR), objective scatter index (OSI), and OQAS values (OVs) at 100%, 20%, and 9% contrast levels were measured preoperatively and 1 day and 1 week after operation using spectral-domain optical coherence tomography and OQAS II, respectively. Best-corrected visual acuity (BCVA) was assessed using the Snellen scale, followed by statistical analysis of its logarithm of the minimal angle of resolution.
RESULTS: There were no significant differences in clinical characteristics between the CEIIS and RL groups. Both groups exhibited notably increased postoperative CMT, MTF cutoff, SR, OV at 100%, 20%, and 9% contrast levels, and reduced OSI, indicating CEIIS and RL improved postoperative visual quality. CEIIS surpassed RL solution in improving postoperative visual quality, decelerating the increase of macular HF numbers and CMT in DM+ patients and postoperative BCVA. There was no difference between CEIIS and RL in long-term vision improvement.
CONCLUSIONS: CEIIS surpasses RL in postoperative visual recovery and retards increases of macular HF numbers and CMT in senior DM+ cataract patients.
摘要：
目的：眼内冲洗液在白内障手术中的应用非常广泛。本文探讨了在非复杂性白内障手术中，由复合电解质眼内冲洗液（CEIIS）或乳酸林格氏液（RL）引起的光学相干断层扫描（OCT）和光学质量分析系统（OQAS）参数之间的差异和关系。
方法：将200例高龄白内障患者随机分为CEIIS组和RL组（N=100例/组）。在超声乳化术中，前房用CEIIS或RL冲洗。将患者细分为糖尿病（DM）组和DM-组。黄斑中心厚度（CMT），超反射焦点(HF),调制传递函数截止频率（MTF截止），斯特雷尔比率(SR)，客观散射指数(OSI)，和OQAS值(OVs)为100%，20%,术前和术后1天和1周使用谱域光学相干断层扫描和OQASII测量9％的对比水平，分别。使用Snellen量表评估最佳矫正视力（BCVA），然后对其最小分辨角的对数进行统计分析。
结果：CEIIS组和RL组的临床特征无显著差异。两组术后CMT均显著增加，MTF截止，SR,OV为100%,20%,和9%的对比度，减少OSI，表明CEIIS和RL改善了术后视觉质量。CEIIS在改善术后视觉质量方面超过RL解决方案，减缓DM+患者和术后BCVA的黄斑HF数量和CMT的增加。CEIIS和RL在长期视力改善方面没有差异。
结论：在老年DM+白内障患者中，CEIIS在术后视力恢复方面超过RL，黄斑HF数量和CMT延迟增加。
方法：将200例高龄白内障患者随机分为CEIIS组和RL组（N=100例/组）。在超声乳化术中，前房用CEIIS或RL冲洗。将患者细分为糖尿病（DM）组和DM-组。黄斑中心厚度（CMT），超反射焦点(HF),调制传递函数截止频率（MTF截止），斯特雷尔比率(SR)，客观散射指数(OSI)，和OQAS值(OVs)为100%，20%,术前和术后1天和1周使用谱域光学相干断层扫描和OQASII测量9％的对比水平，分别。使用Snellen量表评估最佳矫正视力（BCVA），然后对其最小分辨角的对数进行统计分析。
结果：CEIIS组和RL组的临床特征无显著差异。两组术后CMT均显著增加，MTF截止，SR,OV为100%,20%,和9%的对比度，减少OSI，表明CEIIS和RL改善了术后视觉质量。CEIIS在改善术后视觉质量方面超过RL解决方案，减缓DM+患者和术后BCVA的黄斑HF数量和CMT的增加。CEIIS和RL在长期视力改善方面没有差异。
结论：在老年DM+白内障患者中，CEIIS在术后视力恢复方面超过RL，黄斑HF数量和CMT延迟增加。
