PDF(Pubmed)
Abstract：
Leukocyte cell-derived chemotaxin-2 (LECT2) is an important cytokine synthesized by liver. Significant research interest is stimulated by its crucial involvement in inflammatory response, immune regulation, disease occurrence and development. However, bibliometric study on LECT2 is lacking. In order to comprehend the function and operation of LECT2 in human illnesses, we examined pertinent studies on LECT2 investigation in the Web of Science database, followed by utilizing CiteSpace, VOSview, and Scimago Graphica for assessing the yearly quantity of papers, countries/regions involved, establishments, authors, publications, citations, and key terms. Then we summarized the current research hotspots in this field. Our study found that the literature related to LECT2 has a fluctuating upward trend. \"Angiogenesis\", \"ALECT2\", \"diagnosis\", and \"biliary atresia\" are the current investigative frontiers. Our findings indicated that liver diseases (e.g. liver fibrosis and hepatic cell carcinoma), systemic inflammatory disease, and amyloidosis are the current research focus of LECT2. The current LECT2 research outcomes are not exceptional. We hope to promote the scientific research of LECT2 and exploit its potential for clinical diagnosis and treatment of related diseases through a comprehensive bibliometric review.
摘要：
白细胞源性趋化素-2(LECT2)是由肝脏合成的重要细胞因子。它在炎症反应中的关键参与激发了重要的研究兴趣，免疫调节，疾病的发生和发展。然而,缺乏对LECT2的文献计量学研究。为了了解LECT2在人类疾病中的作用和作用，我们检查了WebofScience数据库中有关LECT2调查的相关研究，然后利用CiteSpace,VOSview,和ScimagoGraphica评估每年的论文数量，所涉及的国家/地区，机构,作者,出版物,引文,和关键术语。然后总结了当前该领域的研究热点。我们的研究发现，与LECT2相关的文献有波动上升的趋势。“血管生成”，\"ALECT2\",\"诊断\",和“胆道闭锁”是当前的调查前沿。我们的研究结果表明，肝脏疾病（例如肝纤维化和肝细胞癌），全身性炎症性疾病，和淀粉样变性是目前LECT2的研究热点。目前的LECT2研究结果并不例外。我们希望通过全面的文献计量学综述，促进LECT2的科学研究，挖掘其在临床诊断和治疗相关疾病方面的潜力。
