Abstract:
Mediator, a multiprotein complex, is an important component of the transcription machinery. In plants, the latest reports from our group and some other studies have established that Mediator functions as a signal processor that conveys transcriptional signals from transcription factors to RNA polymerase II. It has been found to be involved in different developmental and stress-adaptation conditions ranging from embryo, root, and shoot development to flowering and senescence and also in response to different biotic and abiotic stresses. In the last one decade, significant progress has been made in understanding the role of Mediator subunits in root development. They have been shown to transcriptionally regulate development of almost all the components of root system architecture - primary root, lateral root and root hair. Their role has also been appreciated in nutrient acquisition through root. In this review, we have discussed all the known functions of Mediator subunits during root development. We have also highlighted the role of Mediator as a nodal point for processing different hormone signaling that regulate root morphogenesis and growth.
摘要:
调解员,多蛋白复合物,是转录机制的重要组成部分。在植物中,我们小组的最新报告和其他一些研究已经确定,Mediator作为一个信号处理器,将转录信号从转录因子传递到RNA聚合酶II.已发现它涉及不同的发育和应激适应条件,从胚胎,根,和芽发育到开花和衰老,以及对不同生物和非生物胁迫的响应。在过去的十年里,在理解Mediator亚基在根系发育中的作用方面取得了重大进展。它们已被证明可以转录调节根系结构几乎所有组件的发育-初级根,侧根和根毛。它们在通过根获得营养方面的作用也得到了赞赏。在这次审查中,我们已经讨论了Mediator亚基在根发育过程中的所有已知功能。我们还强调了Mediator作为处理调节根形态发生和生长的不同激素信号的节点的作用。