Abstract：
Naturally occurring glycosylated hydroquinone Arbutin, has drawn interest due to its possible function in reducing the risk of neurodegenerative diseases such as Huntington\'s disease, amyotrophic lateral sclerosis, Parkinson\'s disease, and Alzheimer\'s disease. Arbutin is well-known for its anti-inflammatory and antioxidant properties, which are essential in preventing oxidative stress and neuroinflammation. Research has shown that arbutin might alter important physiological pathways connected to protein misfolding, synapse function, and neuronal survival processes linked to the development of neurodegenerative diseases. Arbutin can also penetrate the blood- -brain barrier, which increases its therapeutic potential. Arbutin\'s neuroprotective properties and promise as a therapeutic agent for neurodegenerative illnesses are summarized in this review, which also emphasizes the need for further study into the molecular processes behind these effects.
摘要：
天然存在的糖基化氢醌熊果苷，由于其在降低神经退行性疾病如亨廷顿病的风险方面的可能功能，引起了人们的兴趣，肌萎缩侧索硬化，帕金森病,和老年痴呆症。熊果苷以其抗炎和抗氧化特性而闻名，这对预防氧化应激和神经炎症至关重要。研究表明熊果苷可能会改变与蛋白质错误折叠相关的重要生理途径，突触功能，和神经元生存过程与神经退行性疾病的发展有关。熊果苷还能穿透血脑屏障,这增加了它的治疗潜力。本文综述了熊果苷的神经保护特性和作为神经退行性疾病治疗剂的前景。这也强调需要进一步研究这些效应背后的分子过程。
