Abstract：
The term \"comorbid insomnia and sleep apnea\" (COMISA) has been used to categorize the co-occurrence of the most prevalent and impacting sleep disorders. Meanwhile, both insomnia and sleep apnea have been shown to be associated with increased stress levels and cardiometabolic risk, a major cause of mortality. The better knowledge about such convergence would be critical for better understanding pathophysiological pathways and mechanisms. This article provides an overview of epidemiologic aspects, clinical findings, and mechanisms subsiding COMISA. Odontostomatological approach with mandibular advancement devices are discussed as an effective therapeutic approach in these patients.
摘要：
术语“共病失眠和睡眠呼吸暂停”（COMISA）已用于对最普遍和影响最大的睡眠障碍的同时发生进行分类。同时,失眠和睡眠呼吸暂停已被证明与增加的压力水平和心脏代谢风险有关，死亡的主要原因。更好地了解这种融合对于更好地理解病理生理学途径和机制至关重要。这篇文章提供了流行病学方面的概述，临床发现，以及消退COMISA的机制。讨论了使用下颌前移装置的牙颌口腔学方法，作为这些患者的有效治疗方法。
