PDF(Pubmed)
Abstract：
Helicobacter pylori is a microorganism that infects 60% of the population and is considered the main cause of atrophic gastritis, gastric and duodenal ulcers, and gastric cancer. Different emerging pathogens have been found in drinking water and their presence is considered to be an important public health problem. For this reason, it is necessary to carry out the validation of reliable technologies for this type of pathogens and evaluate their performance. This paper reports, for the first time, H. pylori reduction in a drinking water pilot plant of two slow sand filters (SSF). Inlet water was taken from a gravel filtration system of a rural water supply in Colombia and then inoculated with viable cells of H. pylori. By determining the Genomic Units (GU) through quantitative Polymerase Chain Reaction (qPCR), the concentration of GU/sample was measured. In the inlet water amplification for SSF1 and SSF2 were 5.13 × 102 ± 4.48 × 102 and 6.59 × 102 ± 7.32 × 102, respectively, while for the treated water they were 7.0 ± 5.6 and 2.05 × 101 ± 2.9 × 101 GU/sample for SSF1 and SSF2, respectively. The SSF pilot plant reached up to 3 log reduction units of H. pylori; therefore, since there is not an H. pylori contamination indicator and its periodic monitoring is financially complicated, the SSF could guarantee the drinking water quality necessity that exists in rural areas and small municipalities in developing countries, where infection rates and prevalence of this pathogen are high.
摘要：
幽门螺杆菌是一种感染60%人口的微生物，被认为是萎缩性胃炎的主要原因，胃和十二指肠溃疡,还有胃癌.在饮用水中发现了不同的新兴病原体，它们的存在被认为是一个重要的公共卫生问题。出于这个原因,有必要对此类病原体的可靠技术进行验证并评估其性能。本文报告，第一次,在两个慢沙过滤器(SSF)的饮用水试验工厂中减少幽门螺杆菌。入口水从哥伦比亚农村供水的砾石过滤系统中取出，然后接种幽门螺杆菌的活细胞。通过定量聚合酶链反应（qPCR）确定基因组单位（GU），测量GU/样品的浓度。在SSF1和SSF2的进水放大中，分别为5.13×102±4.48×102和6.59×102±7.32×102，而对于处理过的水，SSF1和SSF2分别为7.0±5.6和2.05×101±2.9×101GU/样品。SSF试验工厂达到幽门螺杆菌的3个对数减少单位；因此，由于没有幽门螺杆菌污染指标，并且其定期监测在财务上很复杂，SSF可以保证发展中国家农村地区和小城市存在的饮用水质量必要性，这种病原体的感染率和患病率很高。
