Abstract：
Experiencing peer abuse in childhood can damage mental health, but some people exhibit resilience against these negative outcomes. However, it remains uncertain which specific changes in brain structures are associated with this type of resilience. We categorized 217 participants into three groups: resilience group, susceptibility group, and healthy control group, based on their experiences of peer abuse and mental health problems. They underwent MRI scans to measure cortical thickness in various brain regions of the prefrontal cortex. We employed covariance analysis to compare cortical thickness among these groups. Individuals who resilient to anxiety exhibited smaller cortical thickness in the bilateral inferior frontal gyrus (IFG), and with larger thickness in the right medial orbitofrontal cortex (mOFC), while those resilient to stress was associated with smaller thickness in both the bilateral IFG and bilateral middle frontal gyrus (MFG). These findings deepen our understanding of the neural mechanisms underlying resilience and offer insight into improving individual resilience.
摘要：
童年时期遭受同伴虐待会损害心理健康，但是有些人对这些负面结果表现出韧性。然而,尚不确定大脑结构的哪些特定变化与这种弹性有关。我们将217名参与者分为三组：韧性组，易感性组，健康对照组，根据他们对同伴虐待和心理健康问题的经验。他们接受了MRI扫描，以测量前额叶皮质各个大脑区域的皮质厚度。我们采用协方差分析来比较这些组之间的皮质厚度。对焦虑有弹性的个体在双侧额下回（IFG）表现出较小的皮质厚度，右内侧眶额皮质（mOFC）厚度较大，而那些对应力有弹性的人与双侧IFG和双侧额中回（MFG）的厚度较小有关。这些发现加深了我们对韧性的神经机制的理解，并提供了提高个体韧性的见解。
