Abstract:
The function of endogenous opioids spans from initiating behaviors that are critical for survival, to responding to rapidly changing environmental conditions. A network of interconnected systems throughout the body characterizes the endogenous opioid system (EOS). EOS receptors for beta-endorphin, enkephalin, dynorphin, and endomorphin underpin the diverse functions of the EOS across biological systems. This chapter presents a succinct yet comprehensive summary of the structure of the EOS, EOS receptors, and their relationship to other biological systems.
摘要:
内源性阿片类药物的功能从启动对生存至关重要的行为跨越,以应对快速变化的环境条件。整个身体互连系统的网络表征内源性阿片系统(EOS)。β-内啡肽的EOS受体,脑啡肽,强啡肽,和内吗啡在生物系统中支持EOS的多种功能。本章对EOS的结构进行了简洁而全面的总结,EOS受体,以及它们与其他生物系统的关系。